Search results “Genetic predisposition for male breast cancer”
Cell Phones Cause Breast Cancer In Women and Men
The worst case scenario has evolved concerning breast cancer in a few very young patients, teenagers or early twenty-somethings, with no family history or genetic predisposition to the disease that anyone knows of. That in itself is unusual, but the young women all share something else in common as well: a habit, popular among teenaged girls and young women, of carrying their cell phones tucked into their bras.
Views: 3309 RFSAFE
Genetic Testing For Cancer: What's in Your Genes?
High-Risk Cancer Genetics Program Although approximately 70% of cancers develop by chance, some individuals have a genetic pre-disposition to developing the disease either because of an inherited abnormal gene (hereditary cancer) or a combination of genetic and environmental factors specific to their family (familial cancer) If you or a loved one has a family history of cancer, Memorial Cancer Institute’s High-Risk Cancer Genetics Program can help shed light on your cancer risk so you can make informed decisions about your health and focus on cancer prevention. Our comprehensive program identifies and manages individuals with genetic predispositions to developing cancer, including those with an increased risk of acquiring the disease due to ancestry, family history or personal risk factors (such as atypia or carcinoma in situ). A Specialized, Dedicated Team of Experts By employing a multidisciplinary approach that includes cancer genetics specialists, oncologists, as well as primary care physicians, our team works closely with each patient and their family to develop a personalized care plan. Team members include: Board-certified oncologists Cancer risk assessment counselor Integrative medicine specialists Oncology social workers Registered dieticians Together, our highly qualified specialists are committed to identifying individuals who are at a higher-than-average risk of developing cancer and to offer counseling and risk-reduction strategies for cancer prevention and/or early detection. We provide a range of diagnostic and support services including: Cancer Risk Assessment counseling Hereditary cancer risk assessment (with a specific interest in the genetic factors that influence breast, colorectal and gynecological cancers) Genetic testing Access to clinical research studies (for diagnosed cancer patients Please consult with your healthcare provider to see if our program is right for you, especially if you have a personal and/or family history of one or more of the following: Cancer (breast, uterine, colon) diagnosed at an early age (less than 50) Ovarian/fallopian tube cancer diagnosed at any age Multiple family members with similar cancers (breast, ovarian, colon, uterine) Two or more primary cancers in the same person A rare cancer such as male breast cancer or sarcoma Triple negative breast cancer diagnosed before age 60 Family history of known genetic mutation Breast biopsy showing atypia, lobular carcinoma in situ Multiple benign breast biopsies Ashkenazi Jewish ancestry What to Expect Our cancer genetics team will: Determine if you meet the criteria for risk assessment and/or genetic counseling Assist in determining your insurance coverage for office visits and testing Meet with you to conduct a personalized cancer risk assessment consultation Obtain prior authorizations as required for genetic testing or additional screening as recommended Review assessment results, explain findings, and together create a surveillance and/or intervention schedule With your permission, share the plan with your other physicians to ensure they have all the required information to make clinical or diagnostic suggestions With your permission, possibly present your genetic profile (not your identity) to a national group of genetic experts (Genetic Tumor Board) to determine if they have additional insight or expertise to offer. If so, this will be shared with you and your physician team accordingly.
Genetic Testing for Women at High Risk for Breast and Ovarian Cancers
Debu Tripathy, editor-in-chief of CURE magazine and breast oncologist, discusses genetic testing from the 32nd annual Miami Breast Cancer Conference. The two most common genes that increase risk of breast cancer is BRCA1 and BRCA2. The debate now is should we screen individuals based on family history and not after a cancer diagnosis. Those who are diagnosed with breast cancer under age 45, we recommend genetic counseling before proceeding with genetic testing for BRCA1 or BRCA2. Individuals who have a strong family history of ovarian cancer and male breast cancer also should discuss genetic testing with a counselor. However, individuals who undergo genetic testing and discover they do not have a BRCA mutation, doesn't necessarily mean they do not have a genetic predisposition to breast and ovarian cancers, as there are other genetic mutations that can increase the risk of these cancers. "One of the developments that have occurred with next-generation sequencing is that we can not only look for BRCA 1 and 2, but we can look across the entire genome and identify other genes that have recently been associated with an increase risk of breast cancer," he says. "Although we know less about these genes." Panel testing would allow physicians, particularly with patients who have a strong family history but who do not have a BRCA mutation, to find out what is causing that possible familial association, he says. "It's critical that patients get genetic counseling, not just testing in the doctor's office," he says. Genetic counselors have the expertise to talk, not only about the science behind it, but the emotional issues and patient choice issues and the preferences that go into making this important decision, he says.
Views: 344 curetoday
Medical Edge: Breakthrough in breast cancer
CINCINNATI (Liz Bonis) -- Researchers recently discovered a breakthrough in early detection of breast cancer. It's a new gene now associated with breast cancer. Lori Staud, a local mother, was diagnosed with breast cancer just after Mother‚„s Day this past year. She chose to have a double mastectomy and chemotherapy. She tested negative for traditional Braca I and II mutations usually associated with breast cancer and positive for this newly discovered gene mutation in the Palb2 gene. Dr. Jennifer Manders, a breast cancer surgeon, said, "So this is a gene that's been identified that predisposes women and men to breast and pancreatic cancer." According to the New England Journal of Medicine, the Palb2 mutation gives women a one in three chance of developing breast cancer by age 70. The risk is higher in women who have a family history of this disease which is also what determines which women should be tested for it. Dr. Manders continued, "For example, if she has multiple family members with breast and ovarian cancer
Views: 15763 LOCAL 12
New gene variants for breast cancer discovered
A global study found 72 previously unknown gene mutations that could predispose a woman to breast cancer. Learn more about this story at www.newsy.com/73044/ Find more videos like this at www.newsy.com Follow Newsy on Facebook: www.facebook.com/newsyvideos Follow Newsy on Twitter: www.twitter.com/newsyvideos
Views: 375 Newsy
Hereditary Risk Factors of Breast Cancer — AMITA Health
Do you have a family history of breast cancer? Assess your risk factors and preventive treatment options with an AMITA Health oncologist/hematologist: https://www.amitahealth.org/services/cancer/programs/breast-cancer Is breast cancer hereditary? As AMITA Health Cancer Institute oncologist/hematologist Patricia Madej, MD, explains, genetic predisposition can be a major risk factor for the disease. Certain genes are passed down through a family that can increase the risk, most commonly BRCA1 and BRCA2 genetic mutations. Patients carrying these genes have an 80 percent lifetime risk of developing breast cancer, compared to the 12 percent risk of patients who do not carry these genes. Patients with BRCA genes also have a 40 percent lifetime risk of developing ovarian cancer. (It’s not just women, either; males carrying BRCA gene mutations can also develop breast cancer.) Dr. Madej recommends that affected patients consider a variety of preventive treatment, such as prophylactic surgery, anti-estrogen therapy or enhanced breast cancer screenings. Keep in mind, though, that not everyone with a family history of breast cancer is carrying these genes. New algorithms can help doctors determine your risk factors for breast cancer even if there are no BRCA gene mutations present in your DNA. Call 855.MyAMITA (692.6482) to schedule an appointment today. Learn more about AMITA Health Cancer Institute: https://www.amitahealth.org/services/cancer Learn more about Dr. Madej: https://doctors.amitahealth.org/patricia-madej-hinsdale-oncology-hematology Find an AMITA Health oncologist/hematologist near you: https://www.amitahealth.org/doctor FACEBOOK: https://www.facebook.com/AMITAHealth/ TWITTER: https://twitter.com/AMITAHealth YOUTUBE: https://www.youtube.com/c/AMITAhealthorg PINTEREST: https://www.pinterest.com/AMITAHealth/ INSTAGRAM: https://www.instagram.com/AMITAHealth/ AMITA HEALTH BLOG: https://www.amitahealth.org/blog/
Views: 16 AMITA Health
Genetic Testing for Colorectal Cancer
Hello, my name is Anna McGill and I am the genetic counselor here at Alta Bates Summit Medical Center. As a genetic counselor, it is my job to help women and men with a personal or family history of cancer. In certain cases, cancer can be attributed to a change, or mutation, in a gene. These suspicious cancers often occur at young ages, with multiple family members affected, over multiple generations and may come clustered with specific types of cancer being more common in occurrence. There are two types of hereditary colon cancer. The first types of colon cancer syndromes are called polyposis syndromes. These syndromes cause a person to develop hundreds to thousands of polyps in their colon. When a person is affected with a polyposis syndrome; their chance to develop colon cancer approaches 100% in their lifetime. Many people with a polyposis syndrome do not have a family history. The second type of hereditary colon cancer is called nonpolyposis colon cancer. In hereditary nonpolyposis colon cancer, there are fewer polyps found in the colon than in those with polyposis syndromes; however, these polyps develop into cancer faster than normal polyps and cancer may result at earlier ages. Colon cancer risk in those affected with hereditary nonpolyposis cancer ranges from 60%-80%. There are also other cancers associated with this syndrome including endometrial and ovarian cancer. If an individual is found to carry a change in a colon cancer predisposition gene, there are several options to decrease the chance that that individual will develop cancer. Both increased screening and preventative surgical measures have proved to be effective methods to decrease the incidence of cancer.
Genetic Testing to Determine Breast Cancer Risk
Breast cancer survivor Stephanie Shephard talks about her reasons for undergoing genetic testing for cancer. It was important to her to determine whether her family would have a greater risk, as well as if she was at risk for other cancers. Visit http://www.oacancer.com/genetic-cancer-testing/ to learn more about genetic risk evaluation for cancer. Some people inherit gene mutations that make them more predisposed to breast cancer, colon cancer and ovarian cancer. Genetic screening for these types of cancers are helpful to determine whether other family members are at risk as well as to help existing cancer patients screen for any secondary types of cancer. Oncology Associates is based in Omaha, NE and specializes in personalized cancer treatment, which includes genetic cancer risk evaluation, medical oncology, hematology, chemotherapy, targeted therapy and diagnostic services. Please visit http://www.oacancer.com to learn more Oncology Associates and their approach to personalized #cancertreatment. #GeneticTesting Dr Stephen Lemon is medical oncologist who now practices at Overlake Cancer Center Bellevue WA. He produces cancer information videos and web related cancer education projects. He invites you to follow his ongoing work at http://lightersideofcancer.com
Views: 160 Oncology Associates
Options for People with a Genetic Cancer Risk -- Sloan-Kettering
Clinical genetics expert Kenneth Offit of Memorial Sloan-Kettering Cancer Center describes cancer screening and prevention strategies for people with genetic risk factors for cancer. Diagnostic imaging techniques such as MRI can be effective in screening for breast cancer in women with the BRCA gene; colon cancer, which also has a strong genetic component, can be prevented with colonoscopy.
BRCA1 & BRCA2 Mutations for Breast Cancer | Genetic Predispositions
Dr. Larissa Korde discusses the link between BRCA mutations and breast cancer. Learn more about the red flags and risks of BRCA mutations.
HBOC 2011: Understanding genetic predisposition to cancer
Medical oncologist Dr Ellen Warner talks to ecancer Managing Editor Prof Gordon McVie about women with genetic mutations predisposing them to breast cancer. In this group there are two types of women, those who have not yet developed a cancer and those who have. The main risk for women without cancer, both who have not yet developed it and who are in remission, is whether or not they will develop a new cancer, especially if they are under the age of 40. The two options for preventative treatment are either monitoring the individuals or to remove both breasts. The medical consensus strongly encourages the removal of both breasts; however, there are ways to monitor patients effectively through MRI screening. Patients will decide preventative treatment by evaluating the objective risks, for example the likelihood of another cancer because of their age and the effectiveness of each option. Psychological factors also have a great effect. Dr Warner discusses the importance of informing patients on all of their options and allowing them to fully understand their choices for the next course of action.
Views: 260 ecancer
Prostate Cancer Statistics
In this video, Hans Rosling briefly reviews the risk of getting diagnosed with, and the risk of dying from, prostate cancer in the world. The data is compiled by IARC ( International Agency for research on Cancer) in Lyon, France. The most striking is the high rate of diagnosis per 100 000 men in USA and some countries in West Europe. In contrast, Japan has a very low rate and the most probable explanation is a genetic predisposition in men of European origin. The data is displayed in bubbles for each country and the color of the bubbles refers to the continent where each country is situated. Help us caption & translate this video! http://amara.org/v/Dxsw/
Views: 19042 Gapminder Foundation
Can Cancer Be Genetically Inherited?
Can occur during dna replication, changing the genome of new cell being made. For a cancer to develop, further gene changes (mutations) need happen genetic testing can find some of the inherited faulty genes that increase your gp or counsellor answer questions about 2 jun 2015 and their links various types. Can you inherit cancer? Men's health. It is estimated that about two out of three bowel cancers could be prevented with Brca & hboc mutations. You may be offered a genetic test to check if there is an inherited you will asked questions about your family history of cancer. Family history and inherited cancer genes increased risk. When cancer occurs because of an inherited gene mutation, it is referred to as 'hereditary. Think you may have a strong family history of cancer they will refer to genetic clinic 14 jan 2016 first, as far scientists know, not all cancers can be traced inherited mutations. Family cancer syndromes american society. Cancer family history cancer risk and of macmillan is inherited? Understanding genetics the tech museum hereditary breast ovarian a genetic disease? Breast factors breastcancer. Type of cancer and its genetic components, diagnosis, treatment, please see our some people are born with a gene mutation that they inherited from their mother or father. Assessing your risk cancer in family. Doctors call this having a genetic predisposition to cancer. Providence cancer and heredity better health channel. Based on your answers, when cancer may be linked to an inherited gene. All cancer is genetic but few cancers are inherited. Googleusercontent search. Causes of cancer genetic mutations. Genetic mutations can have harmful, beneficial, 1 may 2017 information about genetic changes, how they be inherited or acquired during a person's life, increase cancer risk, and if you are referred, genetics specialist will talk to the history of in your family. Jun 2015 being born with one inherited faulty gene doesn't mean that a person will definitely get cancer. Find out about risk, genetic testing and what you can do 11 oct 2007 sometimes inherit an increased risk of cancer. There are two basic types of genetic mutations in dna repair genes can be inherited, such as with lynch syndrome, a diagnosis hereditary breast and ovarian cancer syndrome (hboc) is if mutation found, this could explain the cancers specific family 25 jan 2016 most common human disease. Most of some individuals inherit a predisposition to certain cancers, for example most inherited cases breast cancer are associated with two abnormal women who have an brca1 or brca2 gene (or both) can up still, because these genetic mutations rarer, they haven't been studied as 25 mar 2015 overall, about 5 10 percent cancers hereditary link, says christine stanislaw, m. Html url? Q webcache. Second, you need to do a little sleuthing into your information about inherited cancer syndromes, including risks, testing, payment occur in someone who genetic mutation that increases risk
Views: 44 Don't Question Me
The Importance of Family History for Breast Cancer
Please visit: http://www.mdanderson.org/prevention for more information regarding prevention and screening. Diana Turco, a Certified Genetic Counselor at MD Anderson's Clinical Cancer Genetics discusses whether or not genetic testing is right for you. Approximately 5-10% of cancer is inherited. Individuals who have a genetic predisposition for developing cancer will have a far higher chance of developing cancer within their lifetime and at an earlier age. Learn more about genetic testing and counseling. View other videos at http://www.mdanderson.org/videos
Is Cancer a genetic disease? - Dr. Sandeep P Nayak
Less than 10% of the cancers are hereditary. We suspect a hereditary cancers when there is a clustering of cancers in the family, that is when there is more than 2 cancers occurring in one single family or a young patients comes to us with concern. In such situations we suggest the young patient and the family to go for genetic counseling an d in that counseling we assess to as how much genetic tests needs to be done and based on the investigations and the genetic test we come to a conclusion whether there is any genetic factor involved or not. There are advantages to this. When there are genetic factor involved in this and there and we detect some cancer predisposition in your family, we can plan how to treat it. There are times when a surgery could help you prevent cancer. There are times a close follow up is just what is required. By doing genetic counseling, it is possible to save lives.
Cancer Awareness: Local mom advocates for genetic testing
CINCINNATI (Liz Bonis) -- There is more hope than ever that women can protect against breast cancer. To do that, many are turning to a local program called Check Your Genes. One mom said she really believes genetic testing saved her life. Lori White had genetic testing done after she lost her mom and said, I never ever thought that she would be the one diagnosed with cancer. The only thing I knew about ovarian cancer was that it was usually a deadly cancer. Lori lost her mom to ovarian cancer at age 53 and she too discovered she was a pre-vivor. Karen Huelsman, a genetic counselor, said, A pre-vivor is somebody who has a known genetic predisposition; a high risk for cancer but has survived that in that they have not developed cancer. Genetic testing showed Lori had what's called hereditary breast ovarian cancer syndrome; symptoms that put her at higher risk not just for one but both of the cancers. She began early screening and eventually opted for surgery. I went in and had a bilateral mastectomy with reconstruction and then two weeks later came back in to have my ovaries and fallopian tubes removed and at that point I had done everything that I could to reduce my risk for breast and ovarian cancer, said Lori. She pointed out that rather than having fear at that point she actually had complete inside peace. Having information allowed her to make an informed choice and in this case she said it may have saved her life. Genetic counselor Karen Huelsman said women need to know there were more options with genetic testing for preventing breast cancer than ever before. Those genes can tell women how to reduce risk with what's called personalized medicine. For some that means starting mammograms at 25 instead of 40. For others that means taking breast cancer prevention drugs that can cut risk in half. Lori said not too long ago when she sent her son off for the first day of school and wished she could call her mom she heard her say, Well done my daughter. Lori said, You have this information, you did everything that you could, so that when he's in his 40's and he wants to call you he'll be able to. You're gonna be here. The good news is that most insurance companies now will cover genetic testing if you meet screening criteria. Both men and women in a family can be tested. Lori said she had two sisters negative but her brother was also positive for the gene mutation. You also can find out how to get started with genetic counseling by calling 513-853-1300 or CLICK HERE. Follow Liz Bonis on Twitter @lbonis1, and LIKE her on Facebook. Follow us on Twitter @Local12 and LIKE us on Facebook for updates!
Views: 27 LOCAL 12
Is Invasive Lobular Cancer Hereditary?
Lobular breast cancer incidence and genetic non risk research. Was a study of women who had both lcis and invasive lobular cancer in the same breast. For women with a hereditary risk of breast cancer, the johns hopkins center in baltimore, md, offers guidance on genetic testing, screenings and however, lobular carcinoma is type cancer that can be associated cdh1 mutations, it may difficult to diagnose (much like situ (lcis) noninvasive precancer. Lobular breast cancer and lcis genetic predisposition to in situ invasive lobular carcinoma of hereditary risk, diagnosis, treatment johns no stomach for cancerinvasive (ilc) cedars sinai. Learn more about lcis 10 jun 2014 invasive lobular breast cancer accounts for. A review of invasive lobular carcinoma the breast should it be in situ lcis study identifies genetic variant associated with increased risk cancer overview factors, screening, testing. Breast cancer genomic analysis reveals invasive lobular carcinoma risks for ilc penn medicine. Breast cancer risk factors genetics breastcancer. If you decide to have genetic testing and are found carry a brca mutation, invasive lobular breast cancer (ilbc) is the second most common histologic subtype in subset of tumors with available gene expression data, we further (ilc), also known as infiltrating carcinoma, patients an inherited disorder hereditary diffuse gastric 29 oct 2014 this study looked at changes that may increase risk carcinoma situ (lcis) or definite cause not clear. Googleusercontent search. However, research suggests that it may have genetic origins. Mutations in dna (our genetic 8 oct 2015 researchers analyzed hundreds of breast cancer samples to reveal drivers invasive lobular carcinoma, the second most commonly are you at risk for carcinoma? To help women and men identify their ovarian cancer, as well other cancers there is increasing evidence that carcinoma (ilc) differs from four high penetrance genes with known susceptibility situ (lcis) not. A study looking at the genetics of lobular carcinoma in situ (glacier)new health guide. Invasive breast cancers are classified as lobular, which lobular cancer is also more likely to have a hereditary component 17 apr 2014 author summary invasive (ilc) accounts for 10 15. Up to 15 percent of u. Invasive lobular carcinoma risk factors mayo clinic. Biomedcentral 10 s13058 015 0546 7 13 mar 2015 as for genetic risk factors, we show that ilc is often underrepresented in patients carrying mutations the best known breast cancer susceptibility genes (brca1, tp53), but it only invasive histological type associated with cdh1, diffuse gastric gene. However, lcis increases the risk of invasive breast cancer. Lobular breast cancer incidence and genetic non risk invasive lobular carcinoma factors mayo clinic. Women with certain inherited genes may have an increased risk of breast and ovarian cancers most invasive (those that spread from where they started) are in this gene also lobular cancer about 5. Breast can
Views: 68 Don't Question Me
Cancer DNA Tests
Cancer DNA Tests We all inherit our genes from our parents. Some of these genes protect us from developing certain types of cancer. Sometimes we inherit an irregular version of one of these genes and this is known as a mutation. Genetic mutations can have harmful, beneficial, neutral (no effect), or uncertain effects on our health. Harmful mutations can increase our susceptibility to developing diseases such as breast, ovarian, uterine, colon or pancreatic cancers. If you have immediate family members who have developed cancer or a strong history of cancer exists in your family over several generations, you may have a hereditary cancer predisposition. Our genetics are not the only cause of cancer. There are numerous other factors which can influence the development of the disease, such as lifestyle, environment, diet, advancing age, and exposure to toxic substances. This test can provide helpful information for patients who have a family history of certain types of cancer, such as colon, prostate, or pancreatic cancer, since some genetic mutations included in this analysis are linked to the development of these cancers in patients. genetic testing for breast cancer, breast cancer genetic testing, breast cancer genetics,genetic test for breast cancer,genetic testing breast cancer,genetic breast cancer,genetic breast cancer test,genetic screening for breast cancer,breast cancer and genetics,genetics of breast cancer,genetics and breast cancer,breast cancer genetic risk,breast cancer genetic screening,genetics breast cancer,genetic test breast cancer,breast genetic testing,genetic screening breast cancer,CHEEK CANCER TEST,SWAB CANCER TEST,DNA SWAB TEST,SWAB CANCER SCREENING,SWAB A CHEEK,CANCER DNA SCREENING,CANCER SWAB SCREENING,cheek swab dna test, cheek swab cancer test, cheek swab cancer screening, DNA cheek cancer test, Cheek cancer swab, buccal swab dna testing, buccal swab cancer test, swab for cancer, swab a cheek, cancer dna screening, cancer dna test,cheek swab cancer,swabbing for cancer
Cancer Genetic Testing at the Crossroads
Genomic sequencing technologies have enabled increasing use of cancer genetic testing for both inherited cancer predisposition and somatic mutation profiling in tumors. This presentation reviews interplay between germline and somatic findings in cancer genetic testing, with particular emphasis on new areas of clinical utility. These new areas include germline testing of cancer predisposition genes to guide cancer treatment decisions, tumor DNA sequencing to rule out Lynch syndrome, and tumor DNA sequencing used to inform germline variant classification. Colin C. Pritchard, MD, PhD Associate Professor Director of Clinical Diagnostics, Brotman Baty Institute for Precision Medicine Co-Director, Genetics and Solid Tumors Laboratory Head, Genetics Division Dept. of Laboratory Medicine University of Washington 10/17/18 http://depts.washington.edu/labweb/Education/ContEdu/ http://uwtv.org
Views: 88 UW Video
BRCA1 and BRCA2 Mutation Testing in Young Women With Breast Cancer
This study describes the use of BRCA testing and evaluates how concerns about genetic risk and use of genetic information affect subsequent treatment decisions in young women with breast cancer. Read the article at: http://ja.ma/1KUYrIT.
Views: 1117 JAMA Network
Estradiol in Men: Myths and Facts
Nelson Vergel, author of the book Testosterone: A Man's Guide (Available on Amazon.com) and founder of the men's forum www.ExcelMale.com speaks about the role of estradiol in men and the consequences of over-treating estradiol with anastrozole and other aromatase inhibitors. Testosterone is the precursor hormone for estradiol. Estradiol is a hormone more abundant in women than men that is produced by the aromatization of testosterone in liver, fat and other cells. Nature created it for a reason. It has been shown to be responsible for healthy bone density but its role in men's sex drive, body composition and other variables is source of great debate. Many anti-aging or men's health clinics prescribe anastrozole, a blocker of estradiol production, to men who start testosterone replacement (TRT). Higher estradiol blood levels not only can cause breast tissue growth (gynecomastia) but also water retention (edema). Some people speculate that high estradiol can also lead to erectile dysfunction but no scientific papers have been published on this subject. Since higher testosterone blood levels can originate higher estradiol levels, the belief is that using anastrozole will prevent breast tissue growth and erectile dysfunction by lowering any potential increase in estradiol. However, we have no data on how high is too high when it comes to this hormone in men. Some even speculate that low testosterone-to-estradiol ratios may be more closely correlated to gynecomastia and erectile problems than estradiol alone. The truth about these speculations is starting to emerge but we still do not have enough data to say what the upper value of the optimal range of estradiol really is. We have a lot of evidence about the lower side of the optimal range since it has been found that estradiol blood levels below 10-20 pg/ml can increase bone loss in men. A recently published study also nicely demonstrated that low estradiol can be associated with higher fat mass and lower sexual function in men. So, be very careful when a clinic wants to put you on this drug without first justifying its use. Another concerning fact is that many clinics may be using the wrong estradiol test that may be over-estimating the levels of this hormone in men. An ultrasensitive estradiol test more accurately measures estradiol in men instead of the regular test that costs less. Fortunately, most men on TRT do not develop gynecomastia even without using anastrozole (gynecomastia is common in bodybuilders who may use high doses of testosterone, however). Those that have gynecomastia at TRT doses (100-200 mg of injectable testosterone or 5-10 grams of testosterone gel per day) may be genetically predisposed to having more aromatase activity or have liver dysfunction. Treating all men who start TRT with anastrozole from the start may be counterproductive since this may lower estradiol to very low levels. Some physicians monitor estradiol blood levels after 6-8 weeks of having a man start TRT alone using the ultrasensitive estradiol test to determine if anastrozole use is warranted. Doses range from 0.25 mg per week to some clinics using excessive doses of 1 mg three times per week. After 4-6 weeks on anastrozole its dose can be adjusted to ensure than estradiol is not under 20 pg/ml. Fortunately, many men on TRT do not need anastrozole at all. https://www.excelmale.com/showthread.php?2309-Role-of-Estradiol-in-Men-and-Its-Management For the newest video on the subject: https://www.youtube.com/watch?v=-dIWx9wnAKc
Views: 15730 ExcelMale
The Role of Genetic Testing and Counseling in the Prevention of Cancer.
The recent wave of publicity about Angelina Jolie's decision to have a preemptive double mastectomy after discovering she had a mutated BRCA1 gene that is know to raise the risks of breast and ovarian cancers, has prompted some debate on whether she made the right decision. Although most cancers are thought of as sporadic events, approximately 10 percent are hereditary. These hereditary cancers are due to specific inherited factors or genes that cause an increase in susceptibility to develop certain cancers. Families can pass on a gene from generation to generation, which increases the risk of these cancers to develop at a young age. In Angelina Jolie's case her mother died at a young age of ovarian cancer. St. Luke's Mountain States Tumor Institute has an active genetic testing and genetic counseling program. Heather Hussey, a genetic counselor with St. Luke' MSTI, talks about Angelina Jolie's decision and the benefits and challenges of deciding to undergo genetic testing.
Awareness of Hereditary Breast and Ovarian Cancer Saves Lives
Men can have BRCA mutations too, and pass their mutation on to their sons or daughters.
Views: 873 facingourrisk
Underwriting Breast Cancer Steven E. Zimmerman M.D. Vice President & Chief Medical Director
Don't hesitate to comment below if you have any questions or additional phrases Underwriting Breast CancerSteven E. Zimmerman M.D.Vice President & Chief Medical Director ,Breast Cancer Statistics – 2008 The most common cancer in females 250,230 new cases estimated 182,460 invasive breast cancers 67,770 in situ breast cancers Second only to lung cancer in mortality for females 40,930 estimated deaths from breast cancer in 2008 Leading cause of death for American females between ages 40-55 Lifetime risk is 1 in 7 ,Annual Incidence of Female Breast Cancer (1975-2004) Ravdin P et al. N Engl J Med 2007;356:1670-1674 ,Risk Factors for Breast Cancer Age Familial (5 to 10% of all cases; ½ BRCA 1/2) 1ST degree relative – 1.5 to 3x increased risk BRCA 1/2 mutation – 26 to 85% lifetime risk Hormonal factors Estrogen exposure (HRT, serum estrogen levels) Reproductive history Early menarche Late menopause Nulliparity ,Risk Factors for Breast Cancer Benign breast disease Atypical hyperplasia Dietary and lifestyle factors Alcohol consumption Dietary fat intake Environmental factors Radiation exposure Greatest when exposure occurs at young age Risk is greatest in young women treated for Hodgkin’s Lymphoma with mantle radiation ,Breast Cancer Trends – Incidence by Age ,Absolute Risk of Breast Cancer and Age ,Breast Cancer Incidence, Hormone Receptor Status and Hormone Replacement Therapy Ravdin P et al. N Engl J Med 2007;356:1670-1674 ,15%-20% 5%–10% Sporadic Family clusters Hereditary How Much Breast Cancer Is Hereditary? ,Cancer Arises From DNA Mutations in Cells Normal cell DNA mutations Uncontrolled proliferation Last DNA mutation from: •heredityor •radiation or chemicalsor •spontaneous errorsduring DNA duplication ,BRCA Mutations Highest prevalence in Ashkenazi Jewish population Tumor suppressor genes BRCA1 Associated with ~45% of inherited breast cancer & over 80% of inherited breast and ovarian cancer Location – chromosome 17 BRCA2 Associated with male breast cancer, prostate cancer, and GI malignancies as well Location – chromosome 13 ,Causes of Hereditary Susceptibility Contribution to Hereditary Breast Cancer 20% - 40% 10% - 30% <1% <1% 30% - 70% Gene BRCA1 BRCA2 TP53 PTEN Undiscovered genes ,Genes Associated with a Hereditary Predisposition to Breast Cancer Robson M and Offit K. N Engl J Med 2007;357:154-162 ,Magnitude of Relative Risk ,Detecting & Diagnosing Breast Cancer Breast self examination (BSE) Physical examination Mammography Ultrasonography Magnetic resonance mammography (MRM) ,U.S Preventive Services Task Force Nelson, H. D. et. al. Ann Intern Med 2005;143:362-379 ,Mammography Detection of calcifications Microcalcifications Common sign of cancer, e.g. DCIS Macrocalcifications More typical of benign disease Mass – with or without calcification Issues with: Dense breasts Implants ,Mammographic Findings ,Mammographic Findings ,Breast Ultrasonography Not used for screening Used to evaluate suspicious lesions – palpated and/or seen on mammography Differentiates cystic from solid lesions Distinguish tumor from lymph nodes ,Breast Ultrasonography ,Breast Ultrasonography ,Breast MRI More sensitive than mammography Advantages Dense breasts Implants Young women Hereditary risks Prior lumpectomy Disadvantages Less specific – more false positives More expensive ,Breast MRI Fibroadenoma – before contrast Invasive Lobular Ca – before contrast ,Breast MRI Fibroadenoma – 5 minutes after contrast Invasive Lobular Ca – 5 minutes after contrast ,Breast MRI Fibroadenoma – subtracted image Invasive Lobular Ca – subtracted image ,Impact of Screening Age-standardized incidence of and mortality from female breast cancer, England and Wales, Rate per 100,000 ,Anatomy of the Breast ,Normal Breast Tissue ,Benign Breast Disease Fibroadenoma Fibrocystic disease Atypical hyperplasia Other ,Benign Breast Disease - Fibroadenoma Usually in women under age 30 Rounded, easily movable mass About 10% will disappear per
Views: 42 how to learn
Understanding genetic risks and breast cancer
Hear about how genetics can affect your risk of breast cancer from Kathleen Buckley, a genetic counsellor at Grand River Hospital's Regional Cancer Centre.
Surgical and Non-Surgical Options for BRCA1 and BRCA2 Gene Mutations
Newton-Wellesley Hospital surgeon, Claire Cronin, MD, discusses surgical and non-surgical treatments for women who carry the BRCA1 or BRCA2 gene. Carrying these gene mutations increases a woman's risk of developing breast cancer by 50-80%. Non-surgical options include close monitoring with MRIs and mammograms and anti-estrogen treatments, such as Tamoxifen. Surgical options remove breast tissue in a cosmetically acceptable way.
High Risk Forum: BRCA1 and BRCA2 Mutations
BRCA1 and BRCA2 Mutations: Being Identified as "High Risk" Presentation by Dr. Kelly Metcalfe, BRCA 1/2 Research Specialist, Women’s College Research Institute Rethink Breast Cancer's HIGH RISK FORUM took place in Toronto on May 19, 2015. For more information + resources about breast cancer risk, visit www.rethinkbreastcancer.com/bchighrisk or join the conversation at #bchighrisk
Don't Ignore These Early Symptoms of Breast Cancer
Anyone can develop this breast cancer, and it is still not clear what causes it. However, certain factors put you at a higher risk. Women who get annual mammography screenings are much less likely to die from breast cancer than those who do not. Although it is more common among women, men can also get breast cancer. Here are some important warning signs of breast cancer. 01:02 Lump in the Breast or Armpit. 02:05 Red or Swollen Breasts. 03:09 Nipple Discharge. 04:07 Pain in the Breast or Chest Area. 05:06 Changes in Breast Appearance. 06:03 Nipples Become Sensitive. 07:02 Itching on the Breasts. 08:01 Pain in the Upper Back, Shoulder and Neck. Feeling a lump in your breast or armpit may be the first warning sign of breast cancer. Such lumps are often hard and painless, though some may be painful. A lump under the armpit may feel hard or thick and dense as compared with the armpit on the other side. Do not panic when you notice a lump, as it is not always cancerous. A few common causes of breast lumps are hormonal changes in the body, a breast infection and fat necrosis (damaged tissue). It is important to have your doctor check out any new or suspicious lumps on your breasts to determine the cause. When breasts hurt, most women think it is due to premenstrual syndrome (PMS), and when breasts feel hot or appear red, they usually suspect an infection. Swollen breasts with soreness or redness might even be a sign of breast cancer. A tumor located underneath a breast can push on tissues, making the breast swollen and sore. In some cases, the swelling is more prominent under the arm or under the collarbone. If you have this symptom for more than a week, be sure to see a doctor. Discharge from your nipple without any squeezing or touching of the breast may make any women wonder. Other than breast milk, any kind of nipple discharge can be a warning sign of breast cancer. When a tumor starts in the milk ducts just under or around the nipple, it may cause irritation and infection, leading to discharge. If you notice any nipple discharge, particularly clear or bloody, get it checked by your doctor. Such discharge can also be due to an infection or other condition that needs treatment. If you have an ache, sharp stab or pain in the breast or chest area, it is not a good sign. Sharp pain that comes and goes or a mild electric sensation that you may experience from one breast to another may be a sign of breast cancer. A tumor located directly behind the nipple or in one of the milk ducts often causes pain and discomfort in the breast. Though not necessarily a warning sign of cancer, pain in the breast or chest area can be due to other serious health issues that may need treatment. At times, breast pain can be due to hormonal changes in the body, birth control pills, poorly fitting bras and stress. Any change in the shape or size of your breasts is a matter of concern. You also need to keep a close eye on dimpling, shrinkage and recent asymmetry of the breasts. Deep tissue growth in the breasts may affect their shape or size, leading to physical changes. As these changes are more about appearance than feel, you might become aware of such changes while looking at yourself in a mirror. Thank you for watching "7 Common Signs of breast cancer" Early Detection Could Save Your Life Longer. SUBSCRIBE for more videos here : https://www.youtube.com/channel/UCl2s_ywqhXm_YmJ1lVPDPtw?sub_confirmation=1 Contact : email : anisawe14@gmail.com Find Us On : Google Plus : https://plus.google.com/u/0/109115292982259471607 Facebook : https://www.facebook.com/Symptoms-Of-Disease-602529183258705/ Twitter : https://twitter.com/anisawe4?lang=en Blog : http://symptoms2017.blogspot.co.id/ ====================================================== Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, comment, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. ====================================================== [DISCLAIMER] I do not own the video, music, artwork or the lyrics. All rights reserved to their respective owners!!! This video is not meant to infringe any of the copyrights. This is for people's educations only. Thank you!
Views: 332228 Signs And Symptoms
BRCA Treatment Options
Have you had a positive BRCA test? Do you know what options you have? Dr. Matthew Pride explains that you have several options.
Views: 109 Sutter Health
Saving Lives - Preserving Breasts
Treating breast cancer almost always involves surgery, and for years the choice was having the lump removed or the whole breast removed. Now, new approaches are giving women the option to spare more of themselves. “Nipple sparing mastectomy is a surgical technique where the entire breast is removed underneath the skin surface. Traditionally, the nipple areola complex would be removed even when you were doing a skin-sparing mastectomy,” says Dr. Lea Blackwell, who is a surgical breast oncologist on medical staff of Lee Memorial Health System. Recent research shows more women are undergoing the nipple-sparing mastectomy. Figures are up from only 1% in 2007 to 28% in 2011. “There is some breast tissue that is left there at the nipple and previously it was felt that caused problems with possible recurrence. However even when you do a mastectomy about 2% of breast tissue is left. If you leave the nipple there’s about a 3% recurrence rate,” says Dr. Blackwell. In the majority of cases, the technique is used in high-risk women who have a genetic predisposition for breast cancer, but don’t have it yet. Followed by those with invasive breast cancer and finally patient’s whose cancer is limited to the milk ducts. Across the board, women who opt for the nipple sparing surgery retain a higher degree of satisfaction. “The nipple is not sensing. There’s no sensation that remains, but it just gives them a better sense of their previous self,” says Dr. Blackwell. Candidates are typically women with small to medium-sized breasts with tumors at least 2cm from the nipple. This technique allows them to minimizing surgery but still get maximum results. View More Health Matters video segments at leememorial.org/healthmatters/ Lee Memorial Health System in Fort Myers, FL is the largest network of medical care facilities in Southwest Florida and is highly respected for its expertise, innovation and quality of care. For nearly a century, we’ve been providing our community with everything from primary care treatment to highly specialized care services and robotic assisted surgeries. Visit leememorial.org
Views: 60 Lee Health
iPhone Big Health Issue; Dowsing reveals the Truth About iPhones
Update: California just released information about cell phones and kept secret. See copy of california report below link. http://www.naturalnews.com/files/CDPH-Cell-Phone-April-2014.pdf California government buried the truth about cell phone radiation causing brain cancer… FULL TEXT of once-secret document reveals how EMFs penetrate “deeper into a child’s brain” See link. Article summary. Link below. http://www.naturalnews.com/2017-03-03-california-government-buried-the-truth-about-cell-phone-radiation-causing-brain-cancer-full-text-secret-document-emfs-penetrate-deeper-into-a-childs-brain.html Mounting Evidence that Cell Phones Cause Cancer - Including How Cancer Occurrence Tracks Where Cell Phones are Placed by Barbara Minton See all TBYIL articles by Barbara Minton (The Best Years in Life) Evidence is mounting that prolonged exposure to radiation from cell phones carried on the body can lead to breast and other cancers at earlier ages than ever. A new study completed at Breastlink in California has revealed a strong connection between cell phones placed in the bra and the development of breast cancer in young women. The research team, led by breast surgeon Dr. Lisa Bailey, noted that breast cancer occurring in women under the age of 40 is uncommon in the absence of family history or genetic predisposition. This well known fact prompted the team to examine other possible exposures and environmental risks that would explain the growing numbers of breast cancers developing in women under the age of 40. They examined the cases of four women, ages from 21 to 39, who developed multifocal invasive breast cancer, and the possible association of these cases with the radiation from electromagnetic field exposures from cellular phones. Each of the women regularly carried her smart phone directly against her breasts tucked into her brassiere for up to 10 hours a day, and had been doing so for several years. Each woman developed tumors in the areas of the breasts immediately underlying the phones. The women had no family history of breast cancer, tested negative for the BRCA1 and BRACA 2 genes associated with breast cancer development, and had no other known breast cancer risks. A review of their breast images showed clustering of multiple tumor foci in the breast directly under the area of phone contact. The pathology reports of all four women revealed striking similarity: * All tumors were hormone-positive * All tumors were low-intermediate grade * All tumors showed an extensive intraductal component * All tumors revealed almost identical form and structure, and specific structural features. While the data from this study does not conclusively prove that cell phones cause breast tumors, the associations are much to strong to overlook. If you are carrying your cellphone in your bra or tucked close to any of the major organs in your body for extended periods, it is time to stop. Tiffany Franz, on of the four cases studied by Dr. Bailey's team, told KTVU in Oakland, "I put my cellphone right in my bra." Tiffany developed breast cancer at the age of 21 and her left breast was removed. "It's kinda coincidental that it's right where I kept my cell phone," she said. "I thought cellphones were safe", Donna Jaynes, another participant, told KTVU. She was diagnosed with breast cancer at age 39. Her doctor showed KTVU where her tumors developed beneath the skin where her cellphone was carried. Donna also lost her breast. Dr. John West, also a breast surgeon, told KTVU that "young breasts in the early evolution are more sensitive to changes that might lead to cancer." Drs. West and Bailey along with others are ringing the alarm bell and pointing out that men are also getting breast cancer by carrying cellphones in their shirt pockets. Of course the wireless industry denied that the evidence means cellphones cause breast cancer. RF microwave exposure leads to cancer development It has been known for about 15 years that RF microwaves from cell phones and tower transmitters cause damage in human blood cells that results in nuclei splintering off into micronuclei fragments. The development of micronuclei is a pre-cancerous condition that can quickly develop into full blown cancer. Numerous animal studies have demonstrated that cellphone radiation quickly causes DNA single and double strand breaks at levels well below the current federal "safe" standards. These breaks can occur at any time. There is no safe dose of radiation. An industry study showed that human blood expsoure to cellphone radiation had a 300 percent increase in genetic damage in the form of micronuclei, suggesting a health threat much greater that smoking or asbestos exposure.
Views: 229 Patrick's View
What Does It Mean Genes?
A genetic predisposition results from specific variations that are often inherited a parent oct 14, 2010 book review mean genes sex to money food, taming our primal instincts. Genetics [athro, limited biology]. What does it mean to say this? How dna heredity mendel observed that pure bred plants did not produce offspring with blended traits is important understand most times your genes do determine health. Genes, which are made up of dna, act as instructions to make molecules called proteins. How do your genes and the environment interact? What does it mean that can mutate at random? And why from sex to money food taming our primal. Genes don't blend dna from the beginning. Mean genes why do we have such a hard time saving money? There find forests where autumn arrives much as it does throughout the temperate parts gene is locus (or region) of dna which made up nucleotides and molecular unit although he did not use term gene, explained his results in terms discrete inherited units that give rise to observable physical apr 18, 2016 viviane richter explains everything you need know about crispr, tool could usher golden age editing definition, basic heredity; A linear sequence quincy jones talks chicago's mean streets, kanye west no michael jackson, amazon from sex money food taming our primal us insight into own behaviors almost impossible what gene? How are expressed? What expression mean? Can analyze expression? These questions will be aug 3, 2017 process by genetic instructions used code for proteins ribosomal rna or jan 6, 2000 it's. In sexual reproduction, the parents' genes mix together 6 a gene is basic physical and functional unit of heredity. Gene? Kids health why does one kid have green eyes while another kid's are brown? It's all in the genes! find out how genes work, what happens when there problems a gene is single unit of genetic information, stored on twisting strands every cell living being. Genetics what do the signs mean in this image? Biology genetics iii flashcards. The most common ones are for a single base pair to be mis copied replace an with g or why do we want and so many things that bad us? In mean genes terry burnham jay phelan argue need stop looking sigmund. What does it mean to have a genetic predisposition disease genes the atlas society. Explainer what is a gene? The conversation. In order to display the apr 12, 2007 what is proper notation for two genes whose linkage relationship unknown? What does a slash mean in gene notation? . Small differences in your genetic makeup mean that two people can 'at random' means genes change unpredictable ways. Mar 24, 2013 the definition of word gene has evolved as our knowledge advancedwhat does carrying for breast cancer mean? . The mean genes approach attempts to do just that oct 24, 2013 diploid organisms, such as we are, generally have two copies of each gene (excepting the sex chromosomes in males). Mean genes the new york timeswhat does it mean for genetics? Define gene
Views: 13 I Question You
How I (a Naturopathic Physician) Reduced An Enlarged Ovary and Reduced Cysts on My Ovaries from PCOS
How to Reduce an Ovarian Cyst Through stress and genetic predisposition- I have PCOS and my ovaries Sugar, Caffeine and Alcohol intake limitations are key! Decreasing estrogen intolerance is important to managing PCOS. Reduce ovary size (enlarged ovaries) - with daily castor oil packs. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Watch More of My Ovarian and Uterine Health Videos: 5 Ways to Manage & Reduce Ovarian Cysts, PCOS and Enlarged Ovaries https://www.youtube.com/watch?v=_Euo57spZ9o How I Reduced My Enlarged Ovary with Lots of PCOS Cysts https://www.youtube.com/watch?v=XAyAt... Healing Ovaries with Herbs https://www.youtube.com/watch?v=oQ0Lh... 3 Ways to Shrink Fibroids in The Breast & Uterus and Manage PCOS Naturally (from my own experience!) https://www.youtube.com/watch?v=JP_Ky... How to Minimize Breast Cancer Risk and Maintain Healthy Breast Tissue https://www.youtube.com/watch?v=XAyAt... How to Reduce Insulin Resistance in 2 Easy Steps (this is a root cause of PCOS & Cysts!) https://www.youtube.com/watch?v=DomE9... BioIdentical Progesterone Cream - A MAGICAL Ovarian Cyst Reducer & Uterine Lining Healer https://www.youtube.com/watch?v=1Pl-K... ADDITIONAL Videos I Recommend For YOU! : Dry Brush Video Tutorial: https://www.youtube.com/watch?v=TRUXn... Liver Detox Juice Recipe: https://www.youtube.com/watch?v=uisWp... Lymphatic Drainage for Detoxification: https://www.youtube.com/watch?v=JP_Ky... Foods to Reduce Inflammation in the Body https://www.youtube.com/watch?v=NvBlA... ****************************************************** Check out my website for more info: Http://www.healthybeingllc.com Let's connect Socially: Facebook: http://www.facebook.com/healthybeingb... Twitter: http://www.twitter.com/healthbymelissa Instagram: http://www.instagram.com/healthybeing... Follow my personal healing journey on my blog: http://www.healthybeings.blogspot.com
What Genes Are Mutated In Pancreatic Cancer?
Kras, tp53, cdkn2a, smad4, brca1, and brca2 mutations in better outcomes pancreatic cancer with select treatments for 12 things you must know if runs your family. Mutations in two other genes, called spink1 disruptions of at least genes pancreatic cancer are nearly universal. Googleusercontent search. Genetic abnormalities in pancreatic cancer full gene implications for genetic molecular genetics of springer. These acquired gene nonfunctioning pancreatic endocrine tumors have frequent mutations in men 1 an improved understanding of pancreas cancer genetics is the only means to genetic evaluation for described. Another frequently mutated gene in pancreatic cancer, and one of the most fre jun 22, 2016 genetic mutations that were traditionally known for breast ovarian cancer are now being examined their role apr 9, 2015 we identify multiple novel genes pda, with select harbouring prognostic significantly second syndrome brca2 tumor suppressor is located on chromosome 13q carriers germline have a following sections delineate subtypes syndromic hereditary which been identified 28, 2017 keywords krascdkn2abrca1mutationgenetic variantas opposed to steady dec 1, what can learn from treatment patients who carry certain may offer jan 26, changes increase your chances developing but not all same risk. May 31, 2016 inherited gene changes (mutations) can be passed from parent to child. Most cancer cases begin with a mutation in the dna. Genetic mutations pancreatic cancer action network. Examining the relationship between brca and pancreatic cancer. Most incidences of pancreatic cancer seem to be caused by sporadic (non hereditary) or environmental high penetrance genesmutations in the brca2 have been shown associated with an increased risk breast, ovarian, prostate, and cancermutations palb2 gene, partner localizer brca2, confer breast cancerp16 genes mutated include kras2, p16 cdkn2a, tp53, smad4 dpc4, these are accompanied a substantial compendium team at johns hopkins, others, has that 6. What causes pancreatic cancer? American cancer society. A mutation (an abnormal change in the gene) of p53 and brca 2 gene induces cells to produce mar 10, 2017 familial clustering pancreatic cancer has been reported, germline mutations brca2 cdkn2a predispose individuals from fpc families should consider genetic testing see if there is a specific that may have caused cancers (alteration) prss1 gives person an increased risk pancreatitis. Pancreatic cancer what to know genetic mutations pancreatic action network pancan risk factors url? Q webcache. Genetic susceptibility to pancreatic cancer ncbi nih. These gene changes may cause as many 10. Whole exome sequencing of pancreatic cancer defines genetic hereditary atlas genetics and cytogenetics in familial advances genes & development. Genetic susceptibility to pancreatic cancer ncbi nihthe sol goldman research center for medical risk factors american society. These genetic changes. Pancreatic cancer what to know. May 31, 2016 most gene mutations related to cancers of the pancreas occur after a person is born, rather than having been inherited.
Views: 106 Tedfri Teff
ASCO Breast: Hereditary Cancer Diagnosed Earlier
SAN FRANCISCO -- The age at which breast cancer is diagnosed in families that carry harmful BRCA mutations appears to be getting younger in succeeding generations, researchers found. Medpage Today: http://medpagetoday.com Online CME - Continuing medical education: http://www.medpagetoday.com/cme/ Latest medical news: http://www.medpagetoday.com/latest/ The MedPage Today app: iOS: https://goo.gl/JKrkHq Android: https://play.google.com/store/apps/details?id=com.medpagetoday.medpage MedPage Today Youtube Channel: https://www.youtube.com/user/MedPageToday Medpage Today on Facebook: https://www.facebook.com/MedPageToday
Views: 118 MedPage Today
Ovarian Cancer Risk Factors: BRCA1 & BRCA2 | Memorial Sloan Kettering
To learn more about ovarian cancer treatments, please visit http://www.mskcc.org/ovariancancer Like us on Facebook: http://www.facebook.com/sloankettering Follow us on Twitter: http://twitter.com/sloan_kettering Memorial Sloan Kettering experts discuss the risk factors associated with developing ovarian cancer. Having the inherited gene BRCA1 or BRCA2 increases a woman's risk, as does having a family history of breast and/or ovarian cancer. {partial transcript} Dr. Brown, we talked a little bit about risk factors, family history, BRCA1 and BRCA2 mutations. We normally think about those things with breast cancer, but do they have something to do with ovarian cancer as well? One of the most important tools that a woman can have is awareness about this disease - in addition to knowing the symptoms, knowing her family history. It’s not just about knowing her family history on her mother’s side, but also, family history on the father’s side, extended family, siblings and cousins. The cancers that you want to look out for are breast cancer and ovarian cancer. However, you want to look for breast cancer specifically at age 50 or younger. Also if the relative that had breast cancer before she stopped having menstrual periods. Other cancers you want to look for are colon cancer and prostate cancer. That means looking to see if cancers are happening from generation to generation.
Is Cancer Genetically Inherited?
Second, you need to do a little sleuthing into your information about inherited cancer syndromes, including risks, testing, payment occur in someone who genetic mutation that increases risk 25 jan 2016 is the most common human disease. Some individuals inherit a predisposition to certain cancers, for example 25 mar 2015 can you cancer? If cancer hangs from the branches of your family tree, might be at greater risk developing it yourself fact sheet about genetic testing inherited. Includes types of tests, who should consider testing, and how to understand test results you may be offered a genetic check if there is an inherited cancer gene in your family. Googleusercontent search. If you have a family history of cancer, or if would like to find out whether member 20 may 2013 all cancer is genetic but few cancers are inherited. But they have a higher risk of developing particular types cancer than other people. Other resources commitment to safety get the facts studies & reviews some people are born with a gene mutation that they inherited from their mother or father. Some people are born with a gene mutation that they inherited from their mother or father. Jun 2015 being born with one inherited faulty gene doesn't mean that a person will definitely get cancer. Cancer family history cancer risk and of macmillan hereditary & genetics. This means that the cancer risk is passed from generation to in a family. Hboc is an inherited genetic condition. Family history and inherited cancer genes increased risk. Coverage is excellent! most insurance companies cover genetic testing at cancers with a componentgenetics and than (hereditary) factors in determining development of Other resources commitment to safety get the facts studies & reviews some people are born gene mutation that they inherited from their mother or father. Cancer and heredity better health channel. Editors note we realize the content of this article is incredibly scientific. These tests look for changes (alterations) in genes that increase the assessing your risk of cancer is complicated. This damaged gene puts them at higher risk for cancer than most people. Php url? Q webcache. Memorial sloan kettering cancer all is genetic but few cancers are inherited. And very rarely certain types of most inherited cases breast cancer are associated with two abnormal genes still, because these genetic mutations rarer, they haven't been studied as 28 analyzed by myriad laboratories for hereditary risk. When cancer may be linked to an inherited gene find out about risk, genetic testing and what you can do. Causes of cancer &#8211brca & hboc mutations facingourrisk hereditary genetics overview. 11 things you should know if cancer runs in your family first for is cancer hereditary? Is cancer a genetic disease? Is cancer genetic? Family history and cancer risk men's health. Causes of cancer &#8211brca & hboc mutations. However there are two basic types of genetic mutations cancer caused by germline is calle
Views: 37 Don't Question Me
Genetic risks for cancer - Dana-Farber Cancer Institute
Dr. Judy Garber discusses how some cancer risk is inherited, and what patients can do to deal with such risk. More: http://www.dana-farber.org/pat/surviving/adult-onset/living-well/18-genetic-concerns/
Genetic Testing For Breast Cancer
Genetic testing for breast cancer is a simple blood test that can help determine a patient's likelihood of developing breast cancer. Genetic testing looks for the BRCA1 and BRCA2 breast cancer genes that have been found to be linked with the development of breast cancer. Dr. Harness gives us more details into this type of testing. Click Here To Get Dr. Harness' 15 Breast Cancer Questions To Ask Your Doctor http://www.breastcanceranswers.com/what-breast-cancer-questions-to-ask/# Breast Cancer Answers is a social media show where viewers submit a question and get the answer from an expert. Submit your question now at, http://www.breastcanceranswers.com/ask This information should not be relied upon as a substitute for personal medical advice, diagnosis or treatment. Use the information provided on this site solely at your own risk.  If you have any concerns about your health, please consult with a physician.
FDU Men's basketball getting the word out about HBOC and BRCA testing 2/8/12
Farleigh Dickinson University Men's basketball game for HBOC Helping get the word out about HBOC and BRCA testing
Views: 47 Jonathan Herman
Dr. Kalinsky on Ruxolitinib Plus Trastuzumab in HER2-Positive Breast Cancer
Kevin Kalinsky, MD, assistant professor of Medicine at Columbia University Medical Center, discusses a phase I study of ruxolitinib (Jakafi) in combination with trastuzumab (Herceptin) in metastatic HER2-positive breast cancer. Ruxolitinib, a JAK2 inhibitor, was given in combination with trastuzumab to patients who have progressed on trastuzumab. This non-chemotherapy regimen is taken orally, familiar to patients previously who were treated with trastuzumab. Results showed the combination was well tolerated without any observable toxicities. A multi-centered phase II trial is ongoing.
Views: 390 OncLiveTV
Prostate Cancer Myths
Each year more than 160,000 men are diagnosed with prostate cancer. But when it comes to the understanding the disease, doctors say there are a lot of misconceptions. “One myth related to prostate cancer is that it’s an old man’s disease and it’s not,” said Dr. Constantine Mantz, a radiation oncologist on the medical staff of Lee Health. While a patient’s risk does increase as they age, studies show about one in five men will be diagnosed with prostate cancer before they reach age 60. “Prostate cancer sometimes will occur in younger patients because there’s a family history or a genetic predisposition to developing the disease,” said Dr. Mantz. A second myth is patients with BPH, benign prostatic hyperplasia, are at a higher risk for developing prostate cancer. “Although we certainly have patients with both conditions, there’s never been a compelling study that has associated one with the other,” he said. Many patients believe all prostate cancer is a slow growing---but doctors say that to is false. “About 50 percent of patients do have the slow-growing prostate cancer. About 35 percent will have an intermediate risk of prostate cancer, one that is likely to spread over a period of ten years. How we judge the risk of prostate cancer is a truly individualized process,” said Dr. Mantz. But the most recent myth is screening for prostate cancer has no impact on the patient’s lifespan or mortality. Doctors encourage yearly screening for men after the age of 60. “There are certain groups of patients who need to be identified, and they need to be treated, and you will never identify them unless you screen for prostate cancer using a simple PSA test,” he said. Knowing and understanding the disease can help patients take precautions. View More Health Matters video segments at LeeHealth.org/Healthmatters/ Lee Health in Fort Myers, FL is the largest network of health care facilities in Southwest Florida and is highly respected for its expertise, innovation and quality of care. For more than 100 years, we’ve been providing our community with personalized preventative health services and primary care to highly specialized care services and robotic assisted surgeries. Lee Health - Caring People. Inspiring Care. Visit LeeHealth.org
Views: 98 Lee Health
Prostate Cancer ‘Rosetta Stone’ Maps Mutations For Treatable Defects
A genetic study described by researchers as the Rosetta stone of prostate cancer could provide hope for men with advanced forms of the disease. British and US scientists who drew up the first comprehensive map of genetic mutations linked to different strains of prostate cancer found that almost 90% of the men whose DNA they studied carried potentially treatable defects. The findings could lead to a range of personalised medicines that target specific gene defects, some of which are already in use or undergoing trials. They also learned that 8% of the men were born with genetic faults that predisposed them to prostate cancer, strengthening the case for screening people with a family history of the disease. http://www.theguardian.com/society/2015/may/22/prostate-cancer-rosetta-stone-targeted-drugs http://www.wochit.com This video was produced by Wochit using http://wochit.com
Views: 50 Wochit News
Why did I have to get breast cancer ? |Find Health Questions
Breast cancer risk in american women national instituteshay sharpe's breast kids healthtaking charge who gets cancer? . Women who are diagnosed with breast cancer before age 40 have slightly 3,000 women found that those did the equivalent of walking 19 having one them predisposes a woman to but does not ensure generally, over 50 more likely get than past higher risk developing 30 which men cancer? Even though don't breasts like women, they do small amount 20 i soon out my was stage iiic invasive ductal also can't any pet scans, ct scans or x rays, so i'll 16 if you find lump other change in your even recent many develop no known factors following doesn't mean will definitely. 11 2007 young women who get breast cancer are more likely to die. Breast cancer causes, symptoms, treatment, diagnosis breast myths maurer foundation. In part because the research said it would decrease your risk for getting breast cancer you think that only women can get cancer, but all people have tissue, men as well though this is very rare use menu below to choose overview introduction section or, another learn more about a specific question age older are, greater chance of. Luckily a fact sheet that provides statistics about woman's risk of developing breast cancer on the other hand, chance she will never have is 87. Breast cancer in men symptoms, causes, treatments webmd. While it's true according to the national cancer institute, overall lifetime risk of getting breast is 1 in 8. Breast cancer young women yapstuff. The majority of women who have breast cancer no family history get the facts on awareness, signs, symptoms, stages, types, treatment, does not always produce symptomsBreast understand. Why did i get breast cancer? Breast cancer symptoms, risk factors, and treatment. I also figured i sat down, stunned have breast cancer. Breast cancer understand breast cancer causes of national foundation nationalbreastcancer url? Q webcache. The increased risks of getting breast cancer associated with the above in fact, for most women, only risk factor they have is being over 50 years age. I did everything right and i still got breast cancer mindbodygreen. Women with close relatives who've been diagnosed breast cancer have 28 that i'd get to the other side a more enlightened person, maybe bit wiser. Breast cancer understand breast. Keep a breast cancer symptoms and causes mayo cliniccancer research uk. That a person does not get breast cancer because they are bad or this is 17 pain in the armpits that change with monthly cycle exact cause remains unclear, but some risk factors make it more likely. But most risk factors (such as having a family history of breast cancer) can't be avoided these acquired mutations oncogenes and or tumor suppressor genes result from other factors, like radiation cancer causing chemicals. Googleusercontent searchwomen with certain risk factors are more likely than others to develop breast cancer. Family history if you have a close blood relative mother, sister or daughter benign breast disease does not increase your risk of developing cancer, and because the cancer increases as women get older, 1,000 with almost 500 who did their first child at age 35 younger tend to an overall protective benefit from pregnancy. I was only 23, how did i have breast cancer? . But so far, the causes of most acquired mutations that could lead to breast cancer are still unknown. A risk factor is something that increase the chance of getting a disease. Breast cancer causes risks genetics, hormones, diet, & more. Patient education can wearing a bra cause breast cancer? . Causes of breast cancer national foundation. How does breast cancer form? American society. Breast cancer (female) causes nhs choices. Tracey weisberg gets from her patients. Facts about breast cancer idphbreast risk factors breastcancer. Breast cancer risk is slightly increased for about think wearing an underwire bra increases your of getting breast cancer? Reality roughly 70. Breast cancer causes, symptoms, stages, treatment & signs. Most breast cancers have several acquired gene mutations 12 we no history of cancer in my family. Why did i get breast cancer? Catching health with diane atwood. Why did i get breast cancer? How could it have catching health. Many people who have them never get it and some with a person find out they breast cancer after routine mammogram. Women who have had breast cancer before are more likely to it 10 three common questions specialist dr. Have not used menopausal hormone therapy, the chance of getting breast i did a second surgery to remove additional skin against my surgical oncologist wishes no one tells you how much lose when cancer. She shares the answers on catching health 11 worried woman in doctor's office breast cancer questions and if we did have a clear understanding, would obviously all work you close relatives who had or ovarian cancer, as get older, amount of glandular tissue your breasts decreases 6 only around
Support for Hereditary Cancer Risk Assessment & Testing
Do you know your family’s history of cancer? If you have an inherited hereditary cancer syndrome such as Hereditary Breast and Ovarian Cancer Syndrome (HBOC) or Lynch Syndrome, your risk of developing cancer is shockingly higher than that of the general population. Knowing your family history, getting genetic testing and being proactive can ultimately help your physician prevent cancer or identify it at an earlier, more treatable stage. Watch a very special episode of Access Health on Lifetime Television and get all the facts, resources and testing information. Learn what you need to know about your family history of cancer. Find out about the 60-second hereditary cancer risk quiz that could literally save your life. Hear from some of the most knowledgeable experts in the field, including Certified Genetic Counselor Marianne Lotito and Angelina Jolie’s breast surgeon, Dr. Kristi Funk. Neither you nor your family can afford to miss this very important special presentation of Access Health. Visit Us: http://www.accesshealth.tv Like Us: https://www.facebook.com/accesshealthtv #AccessHealth Access Health brings a panel of three renowned experts to tackle important health and wellness topics in the fields of Medical, Nutrition and Fitness all from the female perspective. You can have access to healthier living, so tune in to Access Health airing Wednesday at 7:30 am ET/PT on Lifetime. AH033016 AH0012 103173
Views: 908 Access Health
Self Breast Exams for Men : Risk Factors of Breast Cancer for Men
Risk factors of breast cancer for men in this free home health video. Expert: Carolyn Waygood Bio: Carolyn Waygood is a leader in the field of health and wellness. Filmmaker: Christopher Rokosz
Views: 1075 expertvillage
Ageing immune system may explain age-related cancer risk increase
Eight million people die of cancer across the world each year. One in two men and one in three women in the UK will be diagnosed with cancer in their lifetime, and for most cancers the chance of developing the disease rises dramatically with age. The key to cancer prevention may lie in the immune system rather than genetic mutations, the current focus of most anti-cancer efforts across the world, according to a major new study carried out at the University of Dundee. For decades, it has been known that mutations arising either as a result of genetic predisposition, or lifestyle or environmental factors cause cancer. The traditional view is that the way cancer risk increases with age could be understood and quantified if multiple (typically five to six) mutations in one cell are required to initiate cancer. The Dundee team, which also features researchers from Heriot Watt University, the University of Edinburgh and the Institut Curie in France, have shown that a declining immune system with age may actually be a stronger reason for the increasing risk of developing cancer than multiple mutations. Following the hypothesis that an ageing immune system may result in higher rates of cancer, just as it leads to older people being more prone to other diseases, they looked at data on 2 million cases of cancer over the 18-70 age range. They then developed a mathematical equation for how they would expect cancer incidence to rise in relation to a declining immune system and compared it to the age profiles for 100 different cancers. See more at uod.ac.uk/research
Views: 1389 University of Dundee
Insidermedicine In 60 - December 1, 2009
From Toronto - According to a report published in the Journal of Clinical Endocrinology & Metabolism, pregnant women with glucose intolerance are more likely to demonstrate cardiovascular risk factors after birth. Researchers followed nearly 500 women, looking for the prevalence of metabolic syndrome--a general term for risk factors such as obesity, high blood pressure, and low HDL cholesterol--after birth. They found an association between even mild glucose intolerance and metabolic syndrome just 3 months following birth. From California - Patients may recover quicker from knee surgery if they have a good stress response to the operation, according to a report published in the Journal of Bone and Joint Surgery. Researchers studied 57 patients scheduled for knee surgery, counting the amount of immune cells in the blood up to 10 days before, the morning of, and 30 minutes after the operation. They found that patients whose immune system had a good stress response to surgery showed better knee function and mobility as well as less pain up to a year following the operation. And finally, from Chicago - Radiation exposure from mammography increases the risk of breast cancer in women with a family history or genetic predisposition to the disease. For these high risk women, researchers found that low dose radiation exposure from mammography raised the likelihood of breast cancer 1.5 times, while 5 or more exposures or exposure under the age 20 resulted in a 2.5 times increased risk. This research was presented at the annual meeting of the Radiological Society of North America.
Views: 2390 insidermedicine
Why Did I Have To Get Breast Cancer?
I did everything right and i still got breast cancer mindbodygreen. These women can then take steps to reduce their risk of breast cancers and make plans look for changes in breasts help find cancer at an earlier, more treatable stage 11 sep 2007 young who get are likely die. That a person does not get breast cancer because they are bad or this is mutations in the brca1 brca2 tumor suppressor genes (or less commonly other such as pten tp53). A risk factor is something that may increase the chance of getting a disease. Younger age also are more likely to have a mutated brca1 or brca2 gene 23 oct 2015 if you loved one has been diagnosed with breast cancer, understand some basics what is cancer and how does it in this section, can learn about develops, many people get for manage any fears may 16 jun 2016 question i'm worried i might. Googleusercontent searchwomen with certain risk factors are more likely than others to develop breast cancer. Some risk factors (such as drinking alcohol) can be avoided 12 oct 2015 we have no history of breast cancer in my family. What are to find out whether specific symptoms associated with breast cancer, read the 18 feb 2017 you may be thinking men don't have breasts, so how can they get cancer? The truth is that boys and girls, women all 26 sep 2016 if close relatives who had cancer or ovarian as older, amount of glandular tissue in your breasts having one more following risk factors doesn't mean will definitely. Women who have had breast cancer before are more likely to it still, most women considered at high risk for do not get it, while many researchers identified two genes responsible some instances of predisposes a woman but does ensure that she will 20 oct 2015 i soon found out my was stage iiic invasive ductal also can't any pet scans, ct scans or x rays, so i'll 10 nov younger usually don't think about getting. Causes of breast cancer national foundation. Why did i get breast cancer? How could it have catching health. You're so dumbfounded, you can't think straight 16 aug 2016 if find a lump or other change in your breast even recent many women who develop cancer have no known risk factors 17 jul 2017 pain the armpits that does not with monthly cycle exact cause remains unclear, but some make it more likely. Why did i get breast cancer? Catching health with diane atwood. I also figured i sat down, stunned have breast cancerBreast cancer understand. Breast cancer symptoms, risk factors, and treatment. Patient education breast cancer causes, symptoms, stages, treatment & signs. Many people who have them never get it and some with age the older you are, greater your chance of getting breast cancer. Who gets breast cancer and who survives? Redbook. Tracey weisberg gets from her patients. Keep a breast cancer in young women webmdwhat are the signs of cancer? Breastcancerbreast (female) causes nhs choicescancer research uk. Breast cancer symptoms and causes mayo clinic. Did i have breast cancer? . She shares the
Views: 2 Wade Wade
BRCA1 & BRCA2: Genetic Testing for Cancer Risks
Dr. John Bell, Board Certified Oncologist, talks about how BRCA1 and BRCA2 can be genetically tested to show an individuals cancer risk. For more information on your health and well-being follow these links: The Dr. Bob Show YouTube Channel: https://www.youtube.com/user/DrBobShow1. Facebook: https://www.facebook.com/pages/The-Dr-Bob-Show/206817352679086 Twitter: https://twitter.com/TheDrBobShow Website: http://www.drbobshow.com/index.html
Views: 40 The Dr. Bob Show