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MicroRNA-Based Therapeutics in Cancer - Frank Slack, Harvard Medical School
 
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2nd Annual Nanomedicine Symposium, July 15th 2017, Cambridge MA Frank Slack, Beth Israel Deaconess Medical Center Cancer Center/Harvard Medical School
Cancer and microRNAs, using neuroblastoma to explain
 
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In this video, I dive deep into the world of microRNAs. I explain where they come from, how they mature and what they do. I then apply these principles to explain some of the known pathophysiology of neuroblastoma, focusing on a well-defined microRNA aberration (miRNA-34a associated with 1p deletion) and a newly-discovered microRNA dysfunction (miRNA-128A), both of which are tumour suppressor miRNAs. I also describe what I feel to be an example of excellent scientific research, which goes from the lab to the clinic and back!
The Future of Early Cancer Detection? | Jorge Soto | TED Talks
 
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Along with a crew of technologists and scientists, Jorge Soto is developing a simple, noninvasive, open-source test that looks for early signs of multiple forms of cancer. Onstage at TEDGlobal 2014, he demonstrates a working prototype of the mobile platform for the first time. TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design -- plus science, business, global issues, the arts and much more. Find closed captions and translated subtitles in many languages at http://www.ted.com/translate Follow TED news on Twitter: http://www.twitter.com/tednews Like TED on Facebook: https://www.facebook.com/TED Subscribe to our channel: http://www.youtube.com/user/TEDtalksDirector
Views: 119322 TED
Engineering micro-RNA to cure skin cancer | Larry Zhang | TEDxMileHigh
 
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This talk was given at a local TEDx event, produced independently of the TED Conferences. Can we use micro-RNA to engineer a cure for skin cancer? In this inspiring talk, Larry Zhang shows how he created a new method to inhibit cancer cell growth in squamous cell carcinoma, and shares why "we will never find a cure for cancer." Larry Zhang, a recent high school graduate, has interned for the last three years at a biological research lab at the University of Colorado Boulder, where he is investigating skin cancer development. He is a three-time finalist at the Intel International Science and Engineering Fair for his work on RNA interference and skin cancer regulation. In the fall, he will be studying molecular biology and computer science at MIT in Cambridge, Mass. About TEDx, x = independently organized event In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)
Views: 15799 TEDx Talks
BIDMC investigator, Saumya Das studies microRNA
 
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A cardiovascular research team from Beth Israel Deaconess Medical Center (BIDMC) and Brigham and Women's Hospital (BWH), led by BIDMC Principal Investigator Saumya Das, MD, PhD, has been awarded a $4 million Common Fund grant from the National Institutes of Health (NIH) as part of a newly formed program on Extracellular RNA Communication. The five-year grant will focus on identifying microRNA biomarkers in heart disease.
V. Narry Kim (IBS and SNU) 1: microRNA Biogenesis and Regulation
 
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https://www.ibiology.org/ibioseminars/microrna-biogenesis-regulation.html Part 1: microRNA Biogenesis and Regulation: Narry Kim takes us through the steps in microRNA biogenesis and explains the importance of microRNAs in regulating protein-coding mRNAs. Part 2: Tailing in the Regulation of microRNA and Beyond: Modifications, such as uridylation, of the 3’ tail of both microRNAs and mRNAs can regulate RNA function by targeting it for degradation. Talk Overview: Small RNAs (~20-30 nucleotides in length) are found in many eukaryotes and act to guard against unwanted RNA such as viruses, transposons and mRNAs. One family of small RNAs called microRNAs regulates protein-coding mRNAs by binding to the 3’UTR and repressing translation or inducing mRNA decay. microRNAs play a key role in animal development and diseases such as cancer.  In her first talk, Dr. Narry Kim gives a step-by-step description of the microRNA biogenesis pathway and the points at which the pathway can be regulated. In her second talk, Kim focuses on the regulation of microRNA function. A small percentage of microRNAs are modified with untemplated nucleotides, usually A or U, added to their 3’ end or “tail”. “Tailing” can modify the microRNA function and in some cases it can act as a molecular switch resulting in developmental and pathological transitions.  Kim’s lab was interested in knowing if tailing occurs on other RNAs such as mRNA. They developed a novel method to sequence the 3’ tail region of mRNA allowing them to measure polyA tail length and detect 3’ terminal modifications.  Interestingly, they found widespread uridylation of mRNAs and showed that 3’ polyU modification serves to mark mRNA for decay.   Speaker Biography: Narry Kim is Director of the Institute for Basic Science and a Professor at Seoul National University.  Her lab studies RNA-mediated gene regulation using stem cells, early embryos, and neuronal cells as model systems. Kim received her BA and MS degrees in microbiology from Seoul National University and her DPhil in biochemistry from Oxford University.  She was a postdoctoral fellow at the University of Pennsylvania in Gideon Dreyfuss’ lab before returning to Seoul National University as a faculty member.   Kim is on the editorial board of a number of journals and has helped to organize many meetings on RNA biology.  Her research and contributions to the life sciences community have been recognized with numerous awards including the Women in Science Award from L’Oreal-UNESCO (2008) and the Ho-Am Prize in medicine (2009). In 2014, Kim was elected to the Korean Academy of Science and Technology and the National Academy of Sciences USA.   Learn more about Dr. Kim’s research here: http://www.narrykim.org/en/
Views: 8075 iBiology
The Future of Cancer: Prevention and Precision Medicine
 
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Memorial Sloan Kettering Cancer Center CEO Dr. Craig Thompson tells WSJ’s Simon Constable why he’s optimistic about new therapies aimed at increasing the body’s own ability to fight cancer. Photo: Andrew P. Leonard/Hanna Irie Subscribe to the WSJ channel here: http://bit.ly/14Q81Xy Visit the WSJ channel for more video: https://www.youtube.com/wsjdigitalnetwork More from the Wall Street Journal: Visit WSJ.com: http://online.wsj.com/home-page Follow WSJ on Facebook: http://www.facebook.com/wsjlive Follow WSJ on Google+: https://plus.google.com/+wsj/posts Follow WSJ on Twitter: https://twitter.com/WSJLive Follow WSJ on Instagram: http://instagram.com/wsj Follow WSJ on Pinterest: http://www.pinterest.com/wsj/ Follow WSJ on Tumblr: http://www.tumblr.com/tagged/wall-street-journal Don’t miss a WSJ video, subscribe here: http://bit.ly/14Q81Xy More from the Wall Street Journal: Visit WSJ.com: http://www.wsj.com Visit the WSJ Video Center: https://wsj.com/video On Facebook: https://www.facebook.com/pg/wsj/videos/ On Twitter: https://twitter.com/WSJ On Snapchat: https://on.wsj.com/2ratjSM
Views: 9648 Wall Street Journal
Exercise for Cancer Survivors
 
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Fitness expert Donna Wilson of Memorial Sloan-Kettering explains the benefits of physical activity and demonstrates exercises for cancer survivors. Learn about MSK: https://www.mskcc.org CONNECT WITH MSK Facebook: http://facebook.com/sloankettering Twitter: http://twitter.com/sloan_kettering Instagram: http://instagram.com/sloankettering Request an appointment at MSK by calling 800-525-2225 or online at: https://www.mskcc.org/appointments/request-appointment
MicroRNAs, Biomarkers, NGAL & STEMI
 
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MicroRNAs, Biomarkers, NGAL & STEMI
Breast cancer panel eyes future treatments based on tumor genomic ‘footprint’
 
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Susan Boolbol, MD, FACS New York, NY Dr. Susan Boolbol discusses personalized breast cancer treatment based on tumor genomics. One impact so far: chemotherapy used in far fewer patients. The technology’s ‘footprint’ will continue to grow across cancer therapy. In the future, treatment for varying diseases such as ovarian and breast cancer may even be similar, based on similar genomics.
Views: 155 AmCollegeofSurgeons
RNA interference (RNAi): by Nature Video
 
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RNA interference (RNAi) is an important process, used by many different organisms to regulate the activity of genes. This animation explains how RNAi works and introduces the two main players: small interfering RNAs (siRNAs) and microRNAs (miRNAs). We take you on an audio-visual journey, diving into a cell to show how genes are transcribed to make messenger RNA (mRNA) and how RNAi can silence specific mRNAs to stop them from making proteins. The animation is based on the latest research, to give you an up-to-date view. If you'd like to know more about the structures and processes you see in this video, check out the accompanying slideshow: http://www.nature.com/nrg/multimedia/rnai/animation/index.html Sponsor message (May 2014): Dharmacon RNAi products are now part of GE Healthcare. Learn more at http://www.GELifeSciences.com/Dharmacon
Views: 828726 nature video
TRACO 2014 - MicroRNA and inflammation; Genomics
 
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TRACO 2014 - MicroRNA and inflammation; Genomics Air date: Monday, November 24, 2014, 4:00:00 PM Category: TRACO Runtime: 02:02:15 Description: TRACO Recent advances in understanding cancer biology are beginning to be translated into improvements in diagnosis and treatment of cancer. In the post-genome era, we increasingly rely on strong collaboration between basic and clinical scientists to develop novel approaches for treatment of human disease. The NCI Center for Cancer Research (CCR) is one of the largest cancer research organizations in the world, with more than 200 principal investigators, and has played a major role in development and implementation of many new technologies, such as nanotechnology, next generation sequencing, genomics and proteomics. For more information go to https://ccr.cancer.gov/trainee-resources-courses-workshops-traco Author: C. Harris, NIH; J. Wei, NIH Permanent link: http://videocast.nih.gov/launch.asp?18750
Views: 705 nihvcast
Panel of plasma microRNAs can be measured accurately to detect pancreatic cancer
 
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Panel of plasma microRNAs can be measured accurately to detect pancreatic cancer. Subscribe this channel to watch more motivational, inspirational, valuable and informative videos to soothe, cleanse and inspire your health, mind, body and spirit. Stay tuned and keep watching. Disclaimer:-- Any medical information published on this video is NOT intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. Copyright notice:-- "Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, comment, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational or personal use tips the balance in favor of fair use."
Multitasking microRNA regulates metastasis
 
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Understanding how a tumor switches from sustaining growth in just one part of the body to disseminating secondary tumors throughout the body, a process called metastasis, is a key goal of cancer research. Dr. Robert Weinberg and his colleagues have identified a microRNA that suppresses metastasis at several different stages of the process by virtue of its ability to coordinately target and repress a set of metastasis-promoting genes.
Views: 5970 Cell Press
Camera on Cancer Research: Using Mice Models to Fight Thyroid Cancer
 
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Dr. Sheue-yann Cheng, Head of the Gene Regulation Section in the Laboratory of Molecular Biology, takes you into her lab where she researches the biology and molecular actions of thyroid hormone receptors in health and disease. Dr. Cheng uses mouse models to study resistance to thyroid hormone (RTH), a key step in cancer development. Watch and listen to Dr. Cheng's passion for uncovering possible molecular targets for the treatment of thyroid cancer. Learn more about Dr. Cheng's research at http://ccr.cancer.gov/staff/staff.asp?profileid=5784
Suzanne's Story | Memorial Sloan Kettering
 
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Learn more about Suzanne’s story: https://www.mskcc.org/suzanne Like us on Facebook: http://www.facebook.com/sloankettering Follow us on Twitter: http://twitter.com/sloan_kettering In 2011, Suzanne was diagnosed with small cell cervical cancer – an aggressive cervical cancer. In this short film directed by award-winning filmmaker David Gelb, see how science not only saved her life, but gave her the chance to create a new one. {partial transcript} I always wanted to have three kids. I had the two boys and desperately wanted a girl. I have four brothers and two sons, so my plan was to get married and immediately try to have a baby with Jimmy. Girl please! The first doctor, his exact words to me were: “So, I got the pathology report – there was some cancer there.” The first words out of my mouth were: “Wait – am I going to lose my hair? I’m getting married in four months and I need my hair.” Then I went to the next doctor who scared the hell out of me. Finally, I went to Sloan. I saw her in May that year and her wedding was in September. The specific type of cancer she had is called small cell carcinoma of the cervix, which is very rare. Five-year survival numbers are pretty low. She also wanted to have a child with Jimmy. I was going to do everything I could to make sure those things happened for her, but at the same time realized “man, I hope she’s around for this child.” Doctor Leitao’s first words out of his mouth were: “Don’t Google it.” I never listen, and I don’t know why I listened to him, but I did. I never Googled it. We did this unique procedure called a trachelectomy – it’s only done at a few institutions in the world – it’s for women who have certain types of cervical cancer. Instead of taking out the entire uterus, we take out the cervix itself. Unfortunately for that type of cancer, because of how aggressive it is, we can’t do that.
Views: 588648 Memorial Sloan Kettering
Pancreatic Cancer Research Combining mRNA and miRNA Analysis in a Single Microfluidic Card
 
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Download the app note from this talk here: http://bit.ly/15g6Qnf Dr. Malte Buchholz from the Clinic for Gastroenterology at the University of Marburg, Germany, discusses his pancreatic cancer research in this video. Learn how he measured and analyzed both microRNA and gene expression in the same sample, using a single Custom TaqMan Array Card
Inflammation and Cancer
 
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Lecture given September 2014.
Views: 1001 BradWeeksMD
Help 8-Year-Old Fighting metastatic Neuroblastoma(Stage IV Cancer)
 
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The fundraising link is https://milaap.org/fundraisers/help-bhavanesh-cancer You can do a bank transfer to the below mentioned account setup for this fundraising campaign: UPI: givetosenthilm@yesbankltd Or Account number: 8080811049701 Account name: Senthil Kumar M IFSC code: YESB0CMSNOC Dear Donors, Life wasn’t that easy for me and my family since 2015 onwards. My Child Master. Bhavanesh was diagnosed with Metastatic Neuroblastoma (Childhood Cancer) in May 2015.That moment, I felt the severe pain that my son was gone through. With support of family and friends, I was manage to spend more than 25 Lakhs for his all the treatments available in India. After that treatment also, the disease is still persist in bones as an active lesion. Doctor suggested the option of Anti-GD2 immunotherapy which is the only option available in abroad and it is very costly. They also suggested that the treatment must be done as soon as possible for better results. I decided to try every possibilities for my son’s treatment and his survival. I contacted some hospital in US and UK. The Great Ormond Street Hospital in London for children gave the estimation for the treatment as around 6,00,000 Euros(Around 5.5 crores in our Money)which is not affordable for me. The estimation given by the hospital is also valid for one month. This treatment is only possibility and hope I am having now. He already overcame every challenges in the treatment and the side effects through his courage and willpower .Now also I am believing that, he will get your support for his treatment. Hence, we are positive looking for sponsors to travel and to get that treatment as soon as possible. The estimated total cost of the treatment is between 6,00,000 and 6,50,000 dollars. so, I request all to support my child's treatment by providing possible amount as soon as possible.
Views: 141 AKF Editzz
The Next Wave of Cancer Science | Memorial Sloan Kettering
 
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Two Memorial Sloan Kettering researchers, including Sloan Kettering Institute Director Joan Massagué, share their perspective on the next wave of cancer science.
Mirna TED Talk
 
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Views: 126 Katherine Noll
Polly A. Newcomb: New Colorectal Cancer Precursors: From Microscope to MicroRNA
 
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Polly A. Newcomb Fred Hutchinson Cancer Research Center, Seattle New Colorectal Cancer Precursors: From Microscope to MicroRNA Das Netzwerk gegen Darmkrebs veranstaltete gemeinsam mit dem Deutschen Krebsforschungszentrum (DKFZ), dem Nationalen Centrum für Tumorerkrankungen (NCT), dem Universitätsklinikum Heidelberg und der Felix Burda Stiftung am 5.-6.Juni 2014 den internationalen Expertenworkshop „Innovation in Prevention, Early Detection & Diagnosis of Colorectal Cancer". Führende Wissenschaftler aus USA, UK, Israel, Frankreich, Dänemark und Deutschland stellten ihre neuesten Forschungsergebnisse vor und diskutieren, wie zum Wohle der Patienten Erkenntnisse aus der Wissenschaft -- from Bench to bedside - in den klinischen Alltag überführt werden können. Mehr Informationen: https://www.netzwerk-gegen-darmkrebs.de/2014/06/26/neues-zur-fruherkennung-und-pravention-von-darmkrebs/
AACR: MicroRNAs regulating cancer stem cell self renewal
 
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Dr Michael Clarke - Stanford School of Medicine, USA, speaking at AACR 2009: MicroRNAs regulating self renewal and breast cancer stem cells. Also preventing cancer cells from protecting themselves against radiation.
Views: 1216 ecancer
Using Expression Biomarkers to Improve Pediatric Cancer Care
 
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While not as prevalent as other cancer diseases, every day, 43 children are diagnosed with cancer. Children’s cancer affects all ethnic, gender and socio-economic groups and more than 40,000 children undergo treatment for cancer each year. 12% of children diagnosed with cancer do not survive, while 60% of children who do survive cancer suffer effects in later life, such as infertility, heart failure and secondary cancers. Recurrence rates and secondary complications also occur with pediatric cancer patients - with no current clinically accepted route of testing for these complications, we’ve set out with institutes in Southeast Asia and Taiwan in hopes of identifying fusion gene and microRNA expression biomarkers that can indicate the patient’s risk of recurrence or risk of secondary complications for early intervention and better treatment selection. Through QuarkBio's PanelChip™ Analysis System, we hope that our joint research project can contribute to the ongoing clinical research for pediatric cancer and one day bring better healthcare tools to pediatric cancer patients.
Views: 119 Quark Biosciences
MicroRNA in Human Brain Diseases - Anna M. Krichevsky
 
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Source - http://serious-science.org/videos/1516 Harvard Prof. Anna Krichevsky on role of microRNAs in cell differentiation, oncomiRs, and clinical trials
Views: 1261 Serious Science
Channel 10 London and Kirshenbaum Alzheimer and microRNA Dr Noam Shomron
 
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Channel 10 London and Kirshenbaum Alzheimer and microRNA Dr Noam Shomron לונדון וקירשנבאום מראיינים את ד"ר נועם שומרון על עבודתו בתחום בקרת גנים במחלת האלזהיימר
Views: 230 Noam Shomron
BREAST CANCER: Blood tests available that could catch the disease early
 
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The key to treating Breast Cancer is to catch it early, and and researchers at Arizona State University (ASU) have made a major breakthrough, resulting in a test that could potentially save many lives. FOX 10's John Hook reports.
Views: 1400 FOX 10 Phoenix
G. Blandino - Exploring tumor chemoresistance: miRNAs and cancer stem cells
 
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Giovanni Blandino, Translational Oncogenomic Unit, Regina Elena Cancer Institute, Rome, ITALY speaks on "Exploring tumor chemoresistance: miRNAs and cancer stem cells". This seminar has been recorded by ICGEB Trieste
Views: 95 Icgeb
First microRNA-targeted drug effective for hepatitis C
 
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Miravirsen, the first microRNA-targeted drug to enter human clinical trials, successfully reduced hepatitis C (HCV) RNA levels in patients with chronic HCV infection in a phase 2a trial, according to results published March 27 in the New England Journal of Medicine. The development opens the door to a potential new treatment for the disease. "This is particularly exciting for patients with chronic hepatitis infection," said Gyongyi Szabo, MD, PhD, professor of medicine and a translational scientist studying chronic hepatitis C infection and liver function, who was not involved in the trial. "This may represent a new type of therapy that has the potential for future treatments in patients with the most difficult hepatitis C type to treat -- genotype 1. Especially when one considers that that current treatments have many side effects and limited efficacy." Globally, as many as 170 million people are estimated to suffer from HCV infection. Chronic HCV is a major cause of liver cirrhosis, liver failure, hepatocellular carcinoma and is the leading cause of liver transplants in the United States. Inside the liver, the hepatitis C virus uses a liver-specific microRNA-122 (miR-122) molecule normally important for cholesterol metabolism to replicate. Miravirsen, developed by Santaris Pharma, works by sequestering and effectively inhibiting miR-122 so the virus can't use it to propagate. In the study, a total of 36 patients with chronic HCV genotype 1 received various doses of miravirsen over a 29-day period. Two weeks after treatment, five patients receiving the two highest doses of the drug showed no observable signs of HCV RNA. Essential for turning genes on and off, microRNA was discovered in 1993 by Victor R. Ambros, PhD, the Silverman Chair in Natural Sciences and professor in the Program in Molecular Medicine at UMass Medical School.
Views: 2125 UMass Medical School
New Targets in Breast Cancer Fight
 
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Salk scientists use an old theory to discover new targets in the fight against breast cancer Similarities between genetic signatures in developing organs and breast cancer could predict and personalize cancer therapies Reviving a theory first proposed in the late 1800s that the development of organs in the normal embryo and the development of cancers are related, scientists at the Salk Institute for Biological Studies have studied organ development in mice to unravel how breast cancers, and perhaps other cancers, develop in people. Their findings provide new ways to predict and personalize the diagnosis and treatment of cancer. In a paper published February 3 in Cell Stem Cell, the scientists report striking similarities between genetic signatures found in certain types of human breast cancer and those of stem cells in breast tissue in mouse embryos. These findings suggest that cancer cells subvert key genetic programs that guide immature cells to build organs during normal growth. "Stem cells in a healthy developing embryo have a GPS system to alert them about their position in the organ," says Geoffrey Wahl, a professor in Salk's Gene Expression Laboratory, who led the research. "The system depends on internal instructions and external signals from the environment to tell the stem cell what to do and where to go in the body. It stimulates the stem cells to grow and form more stem cells, or to change into different cells that form complex organs, such as the breast. Our findings tell us that this GPS system is broken during cancer development, and that may explain why we detect stem-like cells in breast cancers."
Views: 1027 Salk Institute
02- Interest in Cancer Biology - Interview with Dr. Frank Slack
 
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For additional information visit http://www.cancerquest.org/frank-slack-interview. Dr. Frank Slack is Professor of Molecular, Cellular & Developmental Biology at Yale University. Dr. Slack's research is directed at understanding the role of microRNAs in cancer, both as possible treatments and as potential targets of therapy. MicroRNAs are small RNA molecules that are normally found in cells. They are able to control the activity of genes and alter the translation of messenger RNAs (mRNAs). The microRNAs present in a normal cell are not exactly the same as those in a cancer cell and that difference could be critical for many cancer types. In this interview, Dr Slack discusses the background to his interest in cancer biology. To learn more about cancer and watch additional interviews, please visit the CancerQuest website at http://www.cancerquest.org.
Views: 249 CancerQuest
New Gene Therapy Developed By MIT May Prevent Cancer Metastasis
 
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Researchers may have identified a new method to prevent surviving cancer cells from spreading to other parts of the body. Early tests at the Massachusetts Institute of Technology, have show a new gene therapy technique, as part of chemotherapy, that uses microsRNAs to prevent breast cancer metastasis. Researchers at the MIT have identified proteins that are important to cell migration and their process of invading healthy organs, successfully blocking cellular processes in their lab experiments and mice. Natalie Artzi, a principal research scientist at MIT said, "The idea is that if the cancer is diagnosed early enough, then in addition to treating the primary tumor with chemotherapy, one could also treat with specific microRNAs, in order to prevent the spread of cancer cells that cause metastasis." http://www.upi.com/Health_News/2016/09/19/MIT-gene-therapy-technique-may-prevent-cancer-metastasis/6061474303828/ http://www.wochit.com This video was produced by YT Wochit News using http://wochit.com
Views: 238 Wochit News
Cancer Cells Programmed Back To Normal Healthy Ones - BTF
 
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Behold The Future...Scientists at the Mayo Clinic in Florida in the Department for Cancer Biology have successfully reprogrammed lung, breast, and bladder cancer cells back into normal, healthy cells by bringing back the function that prevents them from multiplying in excess. While the tests have only been conducted on human cells in the lab (rather than human trial), their work has tremendous implications for the future of cancer treatment. Researchers are hopeful that the technique could one day be used to target tumours, so that the cancer will be “switched off” without the need for chemotherapy, surgery, or other drugs. This important study solves a long-standing biological mystery, but we mustn’t get ahead of ourselves. There’s a long way to go before we know whether these findings, in cells grown in a laboratory, will help treat people with cancer. But it’s a significant step forward in understanding how certain cells in our body know when to grow, and when to stop. Understanding these key concepts is crucial to help continue the encouraging progress against cancer we’ve seen in recent years. – Henry Scowcroft, Cancer Research UK’s senior science information manager When the US researchers added molecules called microRNAs, it stopped the cancer in its tracks. According to Professor Panos Anastasiadis, Chair of the Department for Cancer Biology on Mayo Clinic’s Florida Campus: We can effectively reprogram them (cancer cells) to become and behave as normal. So we can take very aggressive tumour cells that are growing and migrating, replenish them with the microRNAs that are deregulated, and that effectively turn them into normal cells. It’s quite amazing how many discoveries have been made in the last decade alone which show promising results for cancer eradication. Cannabis is a great example. For years, many studies have shown how multiple properties within cannabis completely kill cancerous tumours, yet no clinical trials have been conducted on humans. Despite this fact, a number of people have taken matters into their own hands and have had a tremendous amount of success treating their cancer in this way – Mykayla Comstock is a great example. You can find links to studies that are embedded in various articles that we’ve written on this subject by clicking here. Here is an article we wrote regarding a little known Chinese herb that can kill 12,000 cancer cells for every healthy cell, and a simple Google search would show you just how many vegetables are capable of fighting cancer, broccoli being one great example. The point I am trying to make is that there are a number of ways you can keep healthy. With cancer rates on the rise, at a staggering (approximately) one in two chance of developing the disease in your lifetime, we need to start shifting the conversation and talking about cancer prevention rather than just cancer treatment. And that all starts with looking at our toxic environment. A number of links have been made between cancer and the pesticides that we spray all over our food and the environment. Not to mention the heavy metals in our cosmetics, the Genetically Modified Food, processed food, everyday household products, ingredients within toothpastes and deodorants, and a thousand other consumer goods – we are surrounded by carcinogens on a daily basis. It’s clear that we need to find a better way to do things here. http://www.collective-evolution.com/2015/09/14/big-news-cancer-cells-were-recently-programmed-back-to-normal-healthy-ones/?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+Collective-evolution+%28Collective+Evolution%29 --------------------------------------------------------------------------- Mayo Clinic Researchers Find New Code That Makes Reprogramming of Cancer Cells Possible...Cancer researchers dream of the day they can force tumor cells to morph back to the normal cells they once were. Now, researchers on Mayo Clinic’s Florida campus have discovered a way to potentially reprogram cancer cells back to normalcy. Panos Anastasiadis, Ph.D., chair of the Department of Cancer Biology on Mayo Clinic’s Florida campus comments on the findings which are published in Nature Cell Biology. https://www.youtube.com/watch?t=10&v=yGYTLOGZ40U
Views: 1168 UPHIGH Productions
Serum miRNAs as diagnostic tools in GI malignancies
 
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Dr Goel speaks with ecancertv at WIN 2016 about micro RNAs (miRNAs), and their clinical use as prognostic or diagnostic markers for cancer diagnoses. He reports that RNA fragments isolated from a wide array of sample types can, with thorough assaying, lead to early diagnosis in patients and thus to more effective treatment, especially for those with GI malignancies. Dr Goel discusses how tumour heterogeneity can be monitored and treatments adjusted accordingly, based on miRNA sampling.
Views: 28 ecancer
29. Cancer I
 
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MIT 7.013 Introductory Biology, Spring 2011 View the complete course: http://ocw.mit.edu/7-013S11 Instructor: Tyler Jacks In this lecture, Professor Jacks covers the fundamental definitions of different types of cancers, as well as their stages of progression. License: Creative Commons BY-NC-SA More information at http://ocw.mit.edu/terms More courses at http://ocw.mit.edu
Views: 40802 MIT OpenCourseWare
#880EveryDay Day 1-7 | Deadlifting 880lbs Every Day to Support Kid's Cancer Research
 
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Please visit 880everyday.com to follow along and donate. I am deadlifting 880lbs (400kg) every day for 30 days, or as long as I can make it. We are partnering with Alex's Lemonade Stand, a kid's cancer charity that raises money to fund cancer research specifically for children. It was started by a little girl named Alex when she was 4 years old. She raised over 1 million dollars by age 8 when she passed away from a cancer called Neuroblastoma. Why are we doing this, and why am I using my platform and my company’s platform to do this? Because Kabuki Strength's 4th pillar is Charity, and we believe that making the world a better place through strength should involve giving freely and generously of our time, money, attention, resources, and platform. You can read more about our 4 pillars and our company's philosophy here. Rather than simply drawing attention to ourselves, we’ve found that we can use feats of strength like this to create attention and awareness around a specific cause and have a call-to-action that encourages people to support the cause. My ask of you is simple - please donate whatever you can, if you can, and share one of the daily videos on your platform as a way to reach more people with this cause.  Thank you.
Views: 2007 Chris Duffin
Lung cancer metastasis driven by WNT signaling
 
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Cancer progresses in two stages: growth of a primary tumor followed by spreading of cancer cells to other tissues in the body, a process called metastasis. Metastasis renders cancers more difficult to treat and thus learning how it is regulated is a key goal of cancer research. Dr. Joan Massague and his colleagues show that activation of the WNT signaling pathway regulates the ability of lung tumor cells to spread to the bone and brain. http://www.cell.com
Views: 8877 Cell Press
Professor Max Wicha - Breast cancer stem cell regulation
 
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Professor Max Wicha, Director, University of Michigan Comprehensive Cancer Center Breast cancer stem cell regulation Understanding breast cancer stem cells, how breast cancer tumours recruit stem cells from the bone, and inhibiting receptor CXCR1 using an anti-inflamatory drug to knock out cancer stem cells- a whole new approach
Views: 3629 ecancer
Major Trends in Modern Cancer Research 2012: Discussion with Memorial Sloan-Kettering’s President
 
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Memorial Sloan-Kettering President and CEO Craig B. Thompson welcomes attendees to the seventh annual Major Trends in Modern Cancer Research lecture for high school students and introduces the speakers.
The regulation and activation of P53 functions protect from cancer
 
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Arnold Levine: The regulation and activation of P53 functions by wide variety stress signals protects us from cancers. 4th Annual Meeting of the Israeli Society for Cancer Research The Faculty of Life Science The 2012 Cancer Route -- From Bench to Bedside 8 May 2012, Bar-Ilan University
Views: 6377 barilanuniversity
How are biomarkers used for cancer treatment?
 
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This video is intended for non-US residents. A biomarker indicates the presence or absence of a genetic change in the cancer cells. A prognostic biomarker can indicate what the patient's outcome will be with or without treatment. A predictive biomarker can help to indicate what the patient's outcome will be after he or she has received treatment. For more information on lung cancer and lung cancer treatments, visit: http://www.lifewithlungcancer.info
Views: 13875 LifeWithLungCancer
Inflammation Shuts Down Cancer-Fighting Genes
 
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Chronic inflammation and the chemical silencing of tumor-suppressing genes each play roles in development and progression of colorectal cancer. Research published in Nature Medicine led by MD Anderson Provost Raymond DuBois, M.D., Ph.D., connects the two factors by showing the inflammatory small molecule PGE2 silences genes via DNA methylation. http://www.nature.com/nm/journal/vaop/ncurrent/abs/nm.2608.html
Researching path to better childhood cancer therapies
 
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Jason Shohet, MD, PhD, the Ali and John Pierce Chair of Pediatric Hematology/Oncology, division chief of pediatric hematology and oncology, and associate professor of pediatrics, is focused on developing more effective and less toxic therapies for childhood cancers with a special focus on neuroblastoma. New to his role at UMass Medical School, Dr. Shohet is an accomplished physician-scientist who has contributed significantly to the understanding of the disease through his nearly 20 years of study as co-chair of the Neuroblastoma Research Program at Texas Children’s Cancer Center, Baylor College of Medicine. https://www.umassmed.edu/news/news-archives/2018/10/physician-scientist-jason-shohet-researches-path-to-better-childhood-cancer-therapies/
A cure for Cancer?
 
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http://www.expressoshow.com/ In the world of medicine, scientists are making great strides in the fight against cancer. Using human cells grown in a lab, researchers from the US have figured out a way to stop cancer from growing or spreading. By regulating specific cells within the body called, microRNA’s. Stalk Expresso, we like it! Instagram: @expressoshow Facebook: Expresso Morning Show Twitter: @expressoshow Periscope: @expressoshow
Views: 28 Expresso Show
PREVENTION & REVERSAL OF CANCER- how inflammation promotes cancer- Video 2
 
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Get a better understanding of how inflammation promotes cancer. http://www.healthsynergy.ca This FREE 13 video series will give you a comprehensive understanding of what you can do to prevent and reverse cancer. For decades it's been know that inflammation promotes cancer, thus to prevent cancer, reduce inflammation. There are many sources of hidden inflammation so you need to track them all down and address them accordingly. This video will help you with that. Powerful empowering information you need to know. http://youtu.be/FpnwgRT_DRY
Views: 2708 Robert Ridpath
Treating Cancer-Related Fatigue -- Sloan-Kettering
 
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Patients can fight cancer-related fatigue with a variety of medical and non-medical approaches, says psychiatrist William Breitbart of Memorial Sloan-Kettering Cancer Center. Stimulants such as Ritalin and Provigil, corticosteroids, and sleep aids can be used selectively to increase energy, although they may have side effects. Patients can also boost energy during and after cancer treatment with a modest amount of aerobic exercise, stress reduction, and activities that are relaxing and enjoyable. Learn more about our survivorship services at http://www.mskcc.org/mskcc/html/58022.cfm.
Innate molecules in the inflammation and cancer
 
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Innate molecules in the inflammation and cancer Air date: Wednesday, November 9, 2016, 3:00:00 PM Category: WALS - Wednesday Afternoon Lectures Runtime: 01:02:51 Description: Wednesday Afternoon Lecture Series Dr. Cao has been investigating the molecular mechanisms for innate immune response and inflammation, and trying new approaches to cancer immunotherapy. As corresponding author, he published 226 original papers in peer-reviewed journals including Cell, Nature, Science, Nature Immunology, Immunity, Cancer Cell. Dr. Xuetao Cao is the current President of Chinese Academy of Medical Sciences and Peking Union Medical College. Dr. Cao’s laboratory focuses on the understanding of innate signaling in immunity and inflammation, identification of cell subsets and new molecules in dendritic cell (DC)-initiated immune response and cancer immunotherapy. His group has identified important mediators and regulators of innate signaling, characterized immune subsets with regulatory function in immunity, inflammation and cancer. Dr. Cao has won many awards in recognition of his scientific achievements and dedication to public services and China's medical research and education. He is widely recognized as a thought leader in promoting innovative and cross-disciplinary research at the national level and spearheads a number of initiatives. He is also proud to act as a bridge between China and the world on many occasions and has worked tirelessly to encourage international collaborations and enhance the global visibility of China's own research and development. For more information go to https://oir.nih.gov/wals/2016-2017/innate-molecules-inflammation-cancer Author: Xuetao Cao, M.D., Ph.D., Professor and President, Peking Union Medical College, Professor and President Chinese Academy of Medical Sciences Permanent link: https://videocast.nih.gov/launch.asp?19996
Views: 1605 nihvcast
Making Melanoma Deaths a Thing of the Past | Neil Daly | TEDxWarwick
 
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Neil Daly is an avid follower of innovative health solutions and founder of Skin Analytics, a service which uses an attachment to turn a smartphone into a melanoma diagnostic service. With melanoma the fastest growing cancer worldwide, Skin Analytics provides a low cost solution to identify the disease earlier when treatment is significantly more effective and significantly cheaper - it’s a powerful tool that could - literally - make the difference between life and death! Previously, Neil worked with mobile operators in emerging markets to build mobile money services, providing financial service access to those at the base of the economic pyramid. Neil was also involved in setting up the the worlds first mobile remittance hub. Neil studied Physics at the University of Western Australia before moving to the UK and completing and Executive MBA at London Business School. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at http://ted.com/tedx
Views: 3561 TEDx Talks
Role of Hypoxia in Cancer
 
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Media Project on the effect of PHD1 on Cep192 levels and the regulation of cell cycle progression. This video is based on a Developmental Cell publication by Sonia Rocha, a Principle Investigator in the Centre for Gene Regulation & Expression at the University of Dundee. References Original Research Paper Moser S.C., et al. PHD1 Links Cell-Cycle Progression to Oxygen Sensing through Hydroxylation of the Centrosomal Protein Cep192. Developmental Cell. 2013 Aug 8; 26(4): 381-392. Diagrams Stearns T. The Stearns Lab [Internet]. Stanford University Department of Biology and Genetics [cited 2013 Nov 20]. Available from: http://stearnslab.stanford.edu/WWD.html Ebert S. Mitosis. AP Biology. 2012 Aug 14 [cited 2013 Nov 20]. Available from: http://tinyurl.com/mzfl996 Smith B. Animal Cell Colouring. Smith Life Science [cited 2013 Nov 20]. Available from: http://www.smithlifescience.com/animalcellcolordefine.htm Software Sparkol® Videoscribe Pro. http://www.sparkol.com
Views: 4613 Daniel Bode
Fighting Breast Cancer With Herpes (Brainstorm Ep29)
 
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Website http://qdragon.info/ Shirts and Stuff http://www.zazzle.com/qdragon My twitter http://twitter.com/qdragon Like Brainstorm on Facebook http://www.facebook.com/brainstormnews Medical News http://tinyurl.com/5vjods7 Nanotechnology News http://tinyurl.com/6zposwq Material Science News http://tinyurl.com/5upt4cm Robotics News http://tinyurl.com/4yogedn Assistant Producer http://www.youtube.com/user/Crowbarazar
Views: 1356 Cooking with Q