Search results “Microrna and fighting cancer”
MicroRNA-Based Therapeutics in Cancer - Frank Slack, Harvard Medical School
2nd Annual Nanomedicine Symposium, July 15th 2017, Cambridge MA Frank Slack, Beth Israel Deaconess Medical Center Cancer Center/Harvard Medical School
Detecting Protein and miRNA Cancer Biomarkers
"Detecting Protein and miRNA Cancer Biomarkers using Silicon-based Photonic Crystals and a Resonance Coupling Laser Scanning Instrument" Yafang Tan , Electrical and Computer Engineering CNST Nanotechnology Workshop 2013
Views: 772 NanoBio Node
The Future of Early Cancer Detection? | Jorge Soto | TED Talks
Along with a crew of technologists and scientists, Jorge Soto is developing a simple, noninvasive, open-source test that looks for early signs of multiple forms of cancer. Onstage at TEDGlobal 2014, he demonstrates a working prototype of the mobile platform for the first time. TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design -- plus science, business, global issues, the arts and much more. Find closed captions and translated subtitles in many languages at http://www.ted.com/translate Follow TED news on Twitter: http://www.twitter.com/tednews Like TED on Facebook: https://www.facebook.com/TED Subscribe to our channel: http://www.youtube.com/user/TEDtalksDirector
Views: 118297 TED
Engineering micro-RNA to cure skin cancer | Larry Zhang | TEDxMileHigh
This talk was given at a local TEDx event, produced independently of the TED Conferences. Can we use micro-RNA to engineer a cure for skin cancer? In this inspiring talk, Larry Zhang shows how he created a new method to inhibit cancer cell growth in squamous cell carcinoma, and shares why "we will never find a cure for cancer." Larry Zhang, a recent high school graduate, has interned for the last three years at a biological research lab at the University of Colorado Boulder, where he is investigating skin cancer development. He is a three-time finalist at the Intel International Science and Engineering Fair for his work on RNA interference and skin cancer regulation. In the fall, he will be studying molecular biology and computer science at MIT in Cambridge, Mass. About TEDx, x = independently organized event In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)
Views: 15491 TEDx Talks
Panel of plasma microRNAs can be measured accurately to detect pancreatic cancer
Panel of plasma microRNAs can be measured accurately to detect pancreatic cancer. Subscribe this channel to watch more motivational, inspirational, valuable and informative videos to soothe, cleanse and inspire your health, mind, body and spirit. Stay tuned and keep watching. Disclaimer:-- Any medical information published on this video is NOT intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. Copyright notice:-- "Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, comment, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational or personal use tips the balance in favor of fair use."
Multitasking microRNA regulates metastasis
Understanding how a tumor switches from sustaining growth in just one part of the body to disseminating secondary tumors throughout the body, a process called metastasis, is a key goal of cancer research. Dr. Robert Weinberg and his colleagues have identified a microRNA that suppresses metastasis at several different stages of the process by virtue of its ability to coordinately target and repress a set of metastasis-promoting genes.
Views: 5960 Cell Press
MicroRNA in Human Brain Diseases - Anna M. Krichevsky
Source - http://serious-science.org/videos/1516 Harvard Prof. Anna Krichevsky on role of microRNAs in cell differentiation, oncomiRs, and clinical trials
Views: 1232 Serious Science
Carbs Cause CANCER?! Here's the TRUTH
Let's be transparent about one thing, Xifeng Wu, M.D., Ph.D. says, "the association between glycemic index and lung cancer risk was unclear.” Sources: http://www.nbcchicago.com/news/local/Study-Finds-Carbs-Could-Cause-Lung-Cancer-371392111.html https://www.mdanderson.org/newsroom/2016/03/dietary-glycemic-ind.html CONNECT WITH ME LifestyleWithMe: https://www.youtube.com/channel/UCVi_... Social Media: Instagram: @lifestylewithmarissa Twitter: @marissa_kai Tumblr: http://marissakai.tumblr.com/ Email: lifestylewithmarissa@gmail.com
Views: 2256 MarissaKai
New Gene Therapy Developed By MIT May Prevent Cancer Metastasis
Researchers may have identified a new method to prevent surviving cancer cells from spreading to other parts of the body. Early tests at the Massachusetts Institute of Technology, have show a new gene therapy technique, as part of chemotherapy, that uses microsRNAs to prevent breast cancer metastasis. Researchers at the MIT have identified proteins that are important to cell migration and their process of invading healthy organs, successfully blocking cellular processes in their lab experiments and mice. Natalie Artzi, a principal research scientist at MIT said, "The idea is that if the cancer is diagnosed early enough, then in addition to treating the primary tumor with chemotherapy, one could also treat with specific microRNAs, in order to prevent the spread of cancer cells that cause metastasis." http://www.upi.com/Health_News/2016/09/19/MIT-gene-therapy-technique-may-prevent-cancer-metastasis/6061474303828/ http://www.wochit.com This video was produced by YT Wochit News using http://wochit.com
Views: 225 Wochit News
The Future of Cancer: Prevention and Precision Medicine
Memorial Sloan Kettering Cancer Center CEO Dr. Craig Thompson tells WSJ’s Simon Constable why he’s optimistic about new therapies aimed at increasing the body’s own ability to fight cancer. Photo: Andrew P. Leonard/Hanna Irie Subscribe to the WSJ channel here: http://bit.ly/14Q81Xy Visit the WSJ channel for more video: https://www.youtube.com/wsjdigitalnetwork More from the Wall Street Journal: Visit WSJ.com: http://online.wsj.com/home-page Follow WSJ on Facebook: http://www.facebook.com/wsjlive Follow WSJ on Google+: https://plus.google.com/+wsj/posts Follow WSJ on Twitter: https://twitter.com/WSJLive Follow WSJ on Instagram: http://instagram.com/wsj Follow WSJ on Pinterest: http://www.pinterest.com/wsj/ Follow WSJ on Tumblr: http://www.tumblr.com/tagged/wall-street-journal Don’t miss a WSJ video, subscribe here: http://bit.ly/14Q81Xy More from the Wall Street Journal: Visit WSJ.com: http://www.wsj.com Visit the WSJ Video Center: https://wsj.com/video On Facebook: https://www.facebook.com/pg/wsj/videos/ On Twitter: https://twitter.com/WSJ On Snapchat: https://on.wsj.com/2ratjSM
Views: 9455 Wall Street Journal
Pancreatic Cancer Research Combining mRNA and miRNA Analysis in a Single Microfluidic Card
Download the app note from this talk here: http://bit.ly/15g6Qnf Dr. Malte Buchholz from the Clinic for Gastroenterology at the University of Marburg, Germany, discusses his pancreatic cancer research in this video. Learn how he measured and analyzed both microRNA and gene expression in the same sample, using a single Custom TaqMan Array Card
Making Melanoma Deaths a Thing of the Past | Neil Daly | TEDxWarwick
Neil Daly is an avid follower of innovative health solutions and founder of Skin Analytics, a service which uses an attachment to turn a smartphone into a melanoma diagnostic service. With melanoma the fastest growing cancer worldwide, Skin Analytics provides a low cost solution to identify the disease earlier when treatment is significantly more effective and significantly cheaper - it’s a powerful tool that could - literally - make the difference between life and death! Previously, Neil worked with mobile operators in emerging markets to build mobile money services, providing financial service access to those at the base of the economic pyramid. Neil was also involved in setting up the the worlds first mobile remittance hub. Neil studied Physics at the University of Western Australia before moving to the UK and completing and Executive MBA at London Business School. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at http://ted.com/tedx
Views: 3325 TEDx Talks
TRACO 2014 - MicroRNA and inflammation; Genomics
TRACO 2014 - MicroRNA and inflammation; Genomics Air date: Monday, November 24, 2014, 4:00:00 PM Category: TRACO Runtime: 02:02:15 Description: TRACO Recent advances in understanding cancer biology are beginning to be translated into improvements in diagnosis and treatment of cancer. In the post-genome era, we increasingly rely on strong collaboration between basic and clinical scientists to develop novel approaches for treatment of human disease. The NCI Center for Cancer Research (CCR) is one of the largest cancer research organizations in the world, with more than 200 principal investigators, and has played a major role in development and implementation of many new technologies, such as nanotechnology, next generation sequencing, genomics and proteomics. For more information go to https://ccr.cancer.gov/trainee-resources-courses-workshops-traco Author: C. Harris, NIH; J. Wei, NIH Permanent link: http://videocast.nih.gov/launch.asp?18750
Views: 693 nihvcast
AACR: MicroRNAs regulating cancer stem cell self renewal
Dr Michael Clarke - Stanford School of Medicine, USA, speaking at AACR 2009: MicroRNAs regulating self renewal and breast cancer stem cells. Also preventing cancer cells from protecting themselves against radiation.
Views: 1211 ecancer
A cure for Cancer?
http://www.expressoshow.com/ In the world of medicine, scientists are making great strides in the fight against cancer. Using human cells grown in a lab, researchers from the US have figured out a way to stop cancer from growing or spreading. By regulating specific cells within the body called, microRNA’s. Stalk Expresso, we like it! Instagram: @expressoshow Facebook: Expresso Morning Show Twitter: @expressoshow Periscope: @expressoshow
Views: 28 Expresso Show
Inflammation Shuts Down Cancer-Fighting Genes
Chronic inflammation and the chemical silencing of tumor-suppressing genes each play roles in development and progression of colorectal cancer. Research published in Nature Medicine led by MD Anderson Provost Raymond DuBois, M.D., Ph.D., connects the two factors by showing the inflammatory small molecule PGE2 silences genes via DNA methylation. http://www.nature.com/nm/journal/vaop/ncurrent/abs/nm.2608.html
Camera on Cancer Research: Using Mice Models to Fight Thyroid Cancer
Dr. Sheue-yann Cheng, Head of the Gene Regulation Section in the Laboratory of Molecular Biology, takes you into her lab where she researches the biology and molecular actions of thyroid hormone receptors in health and disease. Dr. Cheng uses mouse models to study resistance to thyroid hormone (RTH), a key step in cancer development. Watch and listen to Dr. Cheng's passion for uncovering possible molecular targets for the treatment of thyroid cancer. Learn more about Dr. Cheng's research at http://ccr.cancer.gov/staff/staff.asp?profileid=5784
Cancer Cells Programmed Back To Normal Healthy Ones - BTF
Behold The Future...Scientists at the Mayo Clinic in Florida in the Department for Cancer Biology have successfully reprogrammed lung, breast, and bladder cancer cells back into normal, healthy cells by bringing back the function that prevents them from multiplying in excess. While the tests have only been conducted on human cells in the lab (rather than human trial), their work has tremendous implications for the future of cancer treatment. Researchers are hopeful that the technique could one day be used to target tumours, so that the cancer will be “switched off” without the need for chemotherapy, surgery, or other drugs. This important study solves a long-standing biological mystery, but we mustn’t get ahead of ourselves. There’s a long way to go before we know whether these findings, in cells grown in a laboratory, will help treat people with cancer. But it’s a significant step forward in understanding how certain cells in our body know when to grow, and when to stop. Understanding these key concepts is crucial to help continue the encouraging progress against cancer we’ve seen in recent years. – Henry Scowcroft, Cancer Research UK’s senior science information manager When the US researchers added molecules called microRNAs, it stopped the cancer in its tracks. According to Professor Panos Anastasiadis, Chair of the Department for Cancer Biology on Mayo Clinic’s Florida Campus: We can effectively reprogram them (cancer cells) to become and behave as normal. So we can take very aggressive tumour cells that are growing and migrating, replenish them with the microRNAs that are deregulated, and that effectively turn them into normal cells. It’s quite amazing how many discoveries have been made in the last decade alone which show promising results for cancer eradication. Cannabis is a great example. For years, many studies have shown how multiple properties within cannabis completely kill cancerous tumours, yet no clinical trials have been conducted on humans. Despite this fact, a number of people have taken matters into their own hands and have had a tremendous amount of success treating their cancer in this way – Mykayla Comstock is a great example. You can find links to studies that are embedded in various articles that we’ve written on this subject by clicking here. Here is an article we wrote regarding a little known Chinese herb that can kill 12,000 cancer cells for every healthy cell, and a simple Google search would show you just how many vegetables are capable of fighting cancer, broccoli being one great example. The point I am trying to make is that there are a number of ways you can keep healthy. With cancer rates on the rise, at a staggering (approximately) one in two chance of developing the disease in your lifetime, we need to start shifting the conversation and talking about cancer prevention rather than just cancer treatment. And that all starts with looking at our toxic environment. A number of links have been made between cancer and the pesticides that we spray all over our food and the environment. Not to mention the heavy metals in our cosmetics, the Genetically Modified Food, processed food, everyday household products, ingredients within toothpastes and deodorants, and a thousand other consumer goods – we are surrounded by carcinogens on a daily basis. It’s clear that we need to find a better way to do things here. http://www.collective-evolution.com/2015/09/14/big-news-cancer-cells-were-recently-programmed-back-to-normal-healthy-ones/?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+Collective-evolution+%28Collective+Evolution%29 --------------------------------------------------------------------------- Mayo Clinic Researchers Find New Code That Makes Reprogramming of Cancer Cells Possible...Cancer researchers dream of the day they can force tumor cells to morph back to the normal cells they once were. Now, researchers on Mayo Clinic’s Florida campus have discovered a way to potentially reprogram cancer cells back to normalcy. Panos Anastasiadis, Ph.D., chair of the Department of Cancer Biology on Mayo Clinic’s Florida campus comments on the findings which are published in Nature Cell Biology. https://www.youtube.com/watch?t=10&v=yGYTLOGZ40U
Views: 1162 UPHIGH Productions
V. Narry Kim (IBS and SNU) 1: microRNA Biogenesis and Regulation
https://www.ibiology.org/ibioseminars/microrna-biogenesis-regulation.html Part 1: microRNA Biogenesis and Regulation: Narry Kim takes us through the steps in microRNA biogenesis and explains the importance of microRNAs in regulating protein-coding mRNAs. Part 2: Tailing in the Regulation of microRNA and Beyond: Modifications, such as uridylation, of the 3’ tail of both microRNAs and mRNAs can regulate RNA function by targeting it for degradation. Talk Overview: Small RNAs (~20-30 nucleotides in length) are found in many eukaryotes and act to guard against unwanted RNA such as viruses, transposons and mRNAs. One family of small RNAs called microRNAs regulates protein-coding mRNAs by binding to the 3’UTR and repressing translation or inducing mRNA decay. microRNAs play a key role in animal development and diseases such as cancer.  In her first talk, Dr. Narry Kim gives a step-by-step description of the microRNA biogenesis pathway and the points at which the pathway can be regulated. In her second talk, Kim focuses on the regulation of microRNA function. A small percentage of microRNAs are modified with untemplated nucleotides, usually A or U, added to their 3’ end or “tail”. “Tailing” can modify the microRNA function and in some cases it can act as a molecular switch resulting in developmental and pathological transitions.  Kim’s lab was interested in knowing if tailing occurs on other RNAs such as mRNA. They developed a novel method to sequence the 3’ tail region of mRNA allowing them to measure polyA tail length and detect 3’ terminal modifications.  Interestingly, they found widespread uridylation of mRNAs and showed that 3’ polyU modification serves to mark mRNA for decay.   Speaker Biography: Narry Kim is Director of the Institute for Basic Science and a Professor at Seoul National University.  Her lab studies RNA-mediated gene regulation using stem cells, early embryos, and neuronal cells as model systems. Kim received her BA and MS degrees in microbiology from Seoul National University and her DPhil in biochemistry from Oxford University.  She was a postdoctoral fellow at the University of Pennsylvania in Gideon Dreyfuss’ lab before returning to Seoul National University as a faculty member.   Kim is on the editorial board of a number of journals and has helped to organize many meetings on RNA biology.  Her research and contributions to the life sciences community have been recognized with numerous awards including the Women in Science Award from L’Oreal-UNESCO (2008) and the Ho-Am Prize in medicine (2009). In 2014, Kim was elected to the Korean Academy of Science and Technology and the National Academy of Sciences USA.   Learn more about Dr. Kim’s research here: http://www.narrykim.org/en/
Views: 7415 iBiology
J. Michael Bishop (UCSF) Part 2: The cancer genome: Challenge and promise
https://www.ibiology.org/human-disease/oncogenes-genetic-paradigm-cancer/#part-2 In part 2 of his lecture, Bishop describes how the sequencing of cancer genomes will advance the study and management of cancer on various fronts, including the discovery of causes, the improvement of early detection, the prediction of outcome and the development of new therapeutics. He stresses the promise of designing therapeutics that can be targeted to those patients most likely to benefit from these drugs.
Views: 5590 iBiology
Inflammation and Cancer
Lecture given September 2014.
Views: 980 BradWeeksMD
MicroRNAs, Biomarkers, NGAL & STEMI
MicroRNAs, Biomarkers, NGAL & STEMI
29. Cancer I
MIT 7.013 Introductory Biology, Spring 2011 View the complete course: http://ocw.mit.edu/7-013S11 Instructor: Tyler Jacks In this lecture, Professor Jacks covers the fundamental definitions of different types of cancers, as well as their stages of progression. License: Creative Commons BY-NC-SA More information at http://ocw.mit.edu/terms More courses at http://ocw.mit.edu
Views: 39407 MIT OpenCourseWare
First microRNA-targeted drug effective for hepatitis C
Miravirsen, the first microRNA-targeted drug to enter human clinical trials, successfully reduced hepatitis C (HCV) RNA levels in patients with chronic HCV infection in a phase 2a trial, according to results published March 27 in the New England Journal of Medicine. The development opens the door to a potential new treatment for the disease. "This is particularly exciting for patients with chronic hepatitis infection," said Gyongyi Szabo, MD, PhD, professor of medicine and a translational scientist studying chronic hepatitis C infection and liver function, who was not involved in the trial. "This may represent a new type of therapy that has the potential for future treatments in patients with the most difficult hepatitis C type to treat -- genotype 1. Especially when one considers that that current treatments have many side effects and limited efficacy." Globally, as many as 170 million people are estimated to suffer from HCV infection. Chronic HCV is a major cause of liver cirrhosis, liver failure, hepatocellular carcinoma and is the leading cause of liver transplants in the United States. Inside the liver, the hepatitis C virus uses a liver-specific microRNA-122 (miR-122) molecule normally important for cholesterol metabolism to replicate. Miravirsen, developed by Santaris Pharma, works by sequestering and effectively inhibiting miR-122 so the virus can't use it to propagate. In the study, a total of 36 patients with chronic HCV genotype 1 received various doses of miravirsen over a 29-day period. Two weeks after treatment, five patients receiving the two highest doses of the drug showed no observable signs of HCV RNA. Essential for turning genes on and off, microRNA was discovered in 1993 by Victor R. Ambros, PhD, the Silverman Chair in Natural Sciences and professor in the Program in Molecular Medicine at UMass Medical School.
Views: 2094 UMass Medical School
G. Blandino - Exploring tumor chemoresistance: miRNAs and cancer stem cells
Giovanni Blandino, Translational Oncogenomic Unit, Regina Elena Cancer Institute, Rome, ITALY speaks on "Exploring tumor chemoresistance: miRNAs and cancer stem cells". This seminar has been recorded by ICGEB Trieste
Views: 88 Icgeb
Analyzing 700+ Germ Cell Seminoma microRNAs | #LabChat
Using a panel of 740 microRNAs to research testicular germ-cell seminomas, Dr. Martin Rijlaarsdam of Erasmus University Medical Center in the Netherlands describes in this LabChat their characterization of unique biomarkers. Want to do a #LabChat with us? https://www.youtube.com/watch?v=zlCKPGTHHlM Dr. Rijlaarsdam’s publication about the novel markers: http://www.ncbi.nlm.nih.gov/pubmed/25382245
2016 Killian Lecture: Tyler Jacks, "Unlocking the Secrets of Cancer"
Lecture title: "Unlocking the Secrets of Cancer" Tyler Jacks, the David H. Koch professor of biology and director of the Koch Institute for Integrative Cancer Research, was MIT’s James R. Killian Jr. Faculty Achievement Award winner for 2015–2016. A pioneering cancer biologist, Professor Jacks was recognized by the committee for his influence on the field of cancer research and for his leadership of MIT’s multidisciplinary cancer research community. Thursday, February 11, 2016 4 pm Huntington Hall (10-250)
Views: 1544 MIT Institute Events
Mirna TED Talk
Views: 124 Katherine Noll
Channel 10 London and Kirshenbaum Alzheimer and microRNA Dr Noam Shomron
Channel 10 London and Kirshenbaum Alzheimer and microRNA Dr Noam Shomron לונדון וקירשנבאום מראיינים את ד"ר נועם שומרון על עבודתו בתחום בקרת גנים במחלת האלזהיימר
Views: 229 Noam Shomron
Exercise for Cancer Survivors
Fitness expert Donna Wilson of Memorial Sloan-Kettering explains the benefits of physical activity and demonstrates exercises for cancer survivors. Learn about MSK: https://www.mskcc.org CONNECT WITH MSK Facebook: http://facebook.com/sloankettering Twitter: http://twitter.com/sloan_kettering Instagram: http://instagram.com/sloankettering Request an appointment at MSK by calling 800-525-2225 or online at: https://www.mskcc.org/appointments/request-appointment
Serum miRNAs as diagnostic tools in GI malignancies
Dr Goel speaks with ecancertv at WIN 2016 about micro RNAs (miRNAs), and their clinical use as prognostic or diagnostic markers for cancer diagnoses. He reports that RNA fragments isolated from a wide array of sample types can, with thorough assaying, lead to early diagnosis in patients and thus to more effective treatment, especially for those with GI malignancies. Dr Goel discusses how tumour heterogeneity can be monitored and treatments adjusted accordingly, based on miRNA sampling.
Views: 26 ecancer
New Targets in Breast Cancer Fight
Salk scientists use an old theory to discover new targets in the fight against breast cancer Similarities between genetic signatures in developing organs and breast cancer could predict and personalize cancer therapies Reviving a theory first proposed in the late 1800s that the development of organs in the normal embryo and the development of cancers are related, scientists at the Salk Institute for Biological Studies have studied organ development in mice to unravel how breast cancers, and perhaps other cancers, develop in people. Their findings provide new ways to predict and personalize the diagnosis and treatment of cancer. In a paper published February 3 in Cell Stem Cell, the scientists report striking similarities between genetic signatures found in certain types of human breast cancer and those of stem cells in breast tissue in mouse embryos. These findings suggest that cancer cells subvert key genetic programs that guide immature cells to build organs during normal growth. "Stem cells in a healthy developing embryo have a GPS system to alert them about their position in the organ," says Geoffrey Wahl, a professor in Salk's Gene Expression Laboratory, who led the research. "The system depends on internal instructions and external signals from the environment to tell the stem cell what to do and where to go in the body. It stimulates the stem cells to grow and form more stem cells, or to change into different cells that form complex organs, such as the breast. Our findings tell us that this GPS system is broken during cancer development, and that may explain why we detect stem-like cells in breast cancers."
Views: 1016 Salk Institute
02- Interest in Cancer Biology - Interview with Dr. Frank Slack
For additional information visit http://www.cancerquest.org/frank-slack-interview. Dr. Frank Slack is Professor of Molecular, Cellular & Developmental Biology at Yale University. Dr. Slack's research is directed at understanding the role of microRNAs in cancer, both as possible treatments and as potential targets of therapy. MicroRNAs are small RNA molecules that are normally found in cells. They are able to control the activity of genes and alter the translation of messenger RNAs (mRNAs). The microRNAs present in a normal cell are not exactly the same as those in a cancer cell and that difference could be critical for many cancer types. In this interview, Dr Slack discusses the background to his interest in cancer biology. To learn more about cancer and watch additional interviews, please visit the CancerQuest website at http://www.cancerquest.org.
Views: 250 CancerQuest
RNAi Therapeutics and Cancer Treatment
©2012 German Science Day Dr. Klaus Giese, Chief Scientific Officer of Silence Therapeutics, presents at the German Science Day on 'The Pre-Clinical and Clinical Development of Atu027, a Liposomal siRNA, for Therapy in Oncology'. Slides for this talk can be found on SlideShare: http://slidesha.re/Atu027_ST Atu027, a novel RNAi therapeutic composed of liposomally formulated siRNA, is currently being tested in a Phase I clinical trial in oncology by Silence Therapeutics. This investigational drug targets the expression of PKN3 in the vascular endothelium and shows inhibition of tumor growth and strong anti-metastatic activity in various pre-clinical models. Latest developments on Atu027 are discussed in the video. For more information, please visit http://www.silence-therapeutics.com Or follow Silence Therapeutics on Twitter @RNAiHub: http://twitter.com/RNAiHub
Views: 3661 Silence Therapeutics
BIDMC investigator, Saumya Das studies microRNA
A cardiovascular research team from Beth Israel Deaconess Medical Center (BIDMC) and Brigham and Women's Hospital (BWH), led by BIDMC Principal Investigator Saumya Das, MD, PhD, has been awarded a $4 million Common Fund grant from the National Institutes of Health (NIH) as part of a newly formed program on Extracellular RNA Communication. The five-year grant will focus on identifying microRNA biomarkers in heart disease.
RNA-Nanoparticles as Carriers of Theraputic miRNA's (Hicham Fenniri, PhD)
2016 George and Angelina Kostas Research Center for Cardiovascular Nanomedicine Annual International Meeting "RNA-Nanoparticles as Carriers of Theraputic miRNA's for the treatment of inflammation and atherosclerotic plaques" Hicham Fenniri, PhD October 13-14, 2016
Cognitive Changes in Patients with Brain Tumors -- Sloan-Kettering
Cognitive (thinking) difficulties are very common in patients with brain cancer. Depending on the location of the tumor, patients may experience problems with attention, organizational skills, memory, or language that often worsen after treatment with radiation or chemotherapy, reports neuropsychologist Denise Correa of Memorial Sloan-Kettering Cancer Center. Cognitive rehabilitation can help patients learn to compensate for these difficulties in their everyday lives. For more information, please visit http://www.mskcc.org/braintumors Learn about MSK: https://www.mskcc.org CONNECT WITH MSK Facebook: http://facebook.com/sloankettering Twitter: http://twitter.com/sloan_kettering Instagram: http://instagram.com/sloankettering Request an appointment at MSK by calling 800-525-2225 or online at: https://www.mskcc.org/appointments/request-appointment
Treating Cancer-Related Fatigue -- Sloan-Kettering
Patients can fight cancer-related fatigue with a variety of medical and non-medical approaches, says psychiatrist William Breitbart of Memorial Sloan-Kettering Cancer Center. Stimulants such as Ritalin and Provigil, corticosteroids, and sleep aids can be used selectively to increase energy, although they may have side effects. Patients can also boost energy during and after cancer treatment with a modest amount of aerobic exercise, stress reduction, and activities that are relaxing and enjoyable. Learn more about our survivorship services at http://www.mskcc.org/mskcc/html/58022.cfm.
Overcoming Drug Resistance to Cancer Therapies
Charles L. Sawyers, MD delivers a lecture on overcoming drug resistance to Cancer therapies, one of a series of lectures from The Yale School of Medicine Bicentennial Symposium, "Biomedicine in the New Century," which took place over April 28--29, 2011.
Views: 6168 YaleUniversity
Prostate Cancer & Endothelin
Mechanism of action of a new strategy to fight prostate cancer: acting on endothelin. Mécanisme d'action d'une nouvelle stratégie thérapeutique pour lutter contre le cancer de la prostate : agir sur l'endothéline. Association website: http://www.efp-online.fr Online education: http://www.invivoveritas.fr
Views: 1608 AssoEFP
Timing Cancer Treatment
Researchers led by members of the Department of Systems Biology at Harvard Medical School had been studying how silencing MDMX, an oncogene, affected the dynamics of p53, a natural tumor suppressor, in cancer cells when they realized those dynamics might affect the cells’ sensitivity to a second, chemotherapy-like treatment. Learn more at https://hms.harvard.edu/news/timing-matters
Metastatic Breast Cancer, Vlog #3
Almost 1 year post metastatic breast cancer diagnosis. Scanxiety is in full effect as I’ve been told that my cancer is probably spreading. This would treatment #2 that hasn’t worked. BUT life is still pretty good & I am still here fighting & living to the fullest.
Views: 14 Mom’s New Normal
The Next Wave of Cancer Science | Memorial Sloan Kettering
Two Memorial Sloan Kettering researchers, including Sloan Kettering Institute Director Joan Massagué, share their perspective on the next wave of cancer science.
PREVENTION & REVERSAL OF CANCER- how inflammation promotes cancer- Video 2
Get a better understanding of how inflammation promotes cancer. http://www.healthsynergy.ca This FREE 13 video series will give you a comprehensive understanding of what you can do to prevent and reverse cancer. For decades it's been know that inflammation promotes cancer, thus to prevent cancer, reduce inflammation. There are many sources of hidden inflammation so you need to track them all down and address them accordingly. This video will help you with that. Powerful empowering information you need to know. http://youtu.be/FpnwgRT_DRY
Views: 2673 Robert Ridpath
Role of Hypoxia in Cancer
Media Project on the effect of PHD1 on Cep192 levels and the regulation of cell cycle progression. This video is based on a Developmental Cell publication by Sonia Rocha, a Principle Investigator in the Centre for Gene Regulation & Expression at the University of Dundee. References Original Research Paper Moser S.C., et al. PHD1 Links Cell-Cycle Progression to Oxygen Sensing through Hydroxylation of the Centrosomal Protein Cep192. Developmental Cell. 2013 Aug 8; 26(4): 381-392. Diagrams Stearns T. The Stearns Lab [Internet]. Stanford University Department of Biology and Genetics [cited 2013 Nov 20]. Available from: http://stearnslab.stanford.edu/WWD.html Ebert S. Mitosis. AP Biology. 2012 Aug 14 [cited 2013 Nov 20]. Available from: http://tinyurl.com/mzfl996 Smith B. Animal Cell Colouring. Smith Life Science [cited 2013 Nov 20]. Available from: http://www.smithlifescience.com/animalcellcolordefine.htm Software Sparkol® Videoscribe Pro. http://www.sparkol.com
Views: 4531 Daniel Bode
The regulation and activation of P53 functions protect from cancer
Arnold Levine: The regulation and activation of P53 functions by wide variety stress signals protects us from cancers. 4th Annual Meeting of the Israeli Society for Cancer Research The Faculty of Life Science The 2012 Cancer Route -- From Bench to Bedside 8 May 2012, Bar-Ilan University
Views: 6349 barilanuniversity
Major Trends in Modern Cancer Research 2012: Discussion with Memorial Sloan-Kettering’s President
Memorial Sloan-Kettering President and CEO Craig B. Thompson welcomes attendees to the seventh annual Major Trends in Modern Cancer Research lecture for high school students and introduces the speakers.
Research Mechanics: Putting the Brakes on Cancer
In this Howard Hughes Medical Institute program, Bert Vogelstein, professor of oncology and pathology at Johns Hopkins University, explains that although there are numerous kinds of cancer, all stem from alterations that allow cell division to outstrip cell demise. Cancers are caused by an accumulation of mutations that alter the activity of genes involved in controlling cell birth, growth, and death. Some of these errors are inherited, but most occur after birth, triggered by environmental carcinogens or by mistakes during cell division. If cancer is likened to a car speeding out of control, cancer-causing mutations are like broken brakes, a stuck accelerator, or an inept mechanic.
Views: 4762 ResearchChannel
Lung cancer metastasis driven by WNT signaling
Cancer progresses in two stages: growth of a primary tumor followed by spreading of cancer cells to other tissues in the body, a process called metastasis. Metastasis renders cancers more difficult to treat and thus learning how it is regulated is a key goal of cancer research. Dr. Joan Massague and his colleagues show that activation of the WNT signaling pathway regulates the ability of lung tumor cells to spread to the bone and brain. http://www.cell.com
Views: 8856 Cell Press