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Why Do the Side Effects of Strattera Continue Even After Quitting?

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The Study: http://www.ncbi.nlm.nih.gov/pubmed/24348020
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Text Comments (105)
Callum Poole (6 days ago)
I’ve been on it for 10 years what the fuck
vbodnariu (1 month ago)
I still wouldnt recommend strattera and would stay away from it completely. Its a shit drug thats probably caused damage to my liver that could causing fatigue.
vbodnariu (1 month ago)
in other words dont take strattera if you are not adhd. By his analogy people with adhd have multiple legged chairs and strattera just gets rid of some of them. That still doesnt mean that it permantly alters the chair forever as even people with adhd have to keep taking these medication to get its effects. in other words some people stop taking strattera and the legs grow back or are restructured causing adhd symptoms to return causing people to want to continue meds.
vbodnariu (1 month ago)
Keep in mind everyone that this does not apply to everyone as we all react diffently to these drugs but this is important information.
Olink (1 month ago)
Took em for three months. Stopped because of headaches, and now after three more months still got em, although a little less severe. But still, severe enough. I wish I never took that shit.
LegendaryGamingChannel (23 days ago)
Olink I took it and it changed my gender and I’m dying I think
Max Pfeifer (2 months ago)
oh my god i just wish it wouldnt be so hard to get my doc to prescribe amphetamine instead
Rosan Sashida (3 months ago)
Can somebody translate this to me in a more simple form?!
Nicola Dias (4 months ago)
So basically it'll take anyone ages to recover from the damage the Strattera has caused... That is absolutely brilliant to hear.
Yeababy (4 months ago)
Maybe the changes are good for a fucked up adhd brain?
Yeababy (4 months ago)
Sons of Apollo Opinion on other less potentially harmful approach to treat adhd? I know amphetamines are considered neurotoxic in higher doses.
Sons of Apollo (4 months ago)
That is the hope.
BobbyJoeXForgotenSB (6 months ago)
its been over 10 years and i developed permanent side effects and possibly permanent disorders from this drug
DIVADTHEODD (1 month ago)
I know this comment is dated but, how long did you take strattera? I’ve been on it for 3 months now and am hating it due to the side effects.
agaragar21 (1 month ago)
Details please ...?
John Doe (7 months ago)
Sheeople. May as well give your kids dmt
Sebastian Boynton (7 months ago)
So would you say that it's side effects are worse and more permanent than vyvance?
Rigknot (8 months ago)
This scared the shit out of me more than a scary movie
FLORIDAJESUSBOY 777 (18 days ago)
Tanisha Raines I’m dead serious
FLORIDAJESUSBOY 777 (18 days ago)
Qwape ain’t no telling how long they will last. Just stay completely away!!!! From these pills
Tanisha Raines (19 days ago)
+FLORIDAJESUSBOY 777 woah for real 😮
Qwape (2 months ago)
+FLORIDAJESUSBOY 777 And for how long will those side effects last?
Qwape (2 months ago)
But this shortness of breath is getting better. I would be so glad if you could help me out of this hell.
Courtney Smith (8 months ago)
I like your channel. What is your background?
majd alomari (10 months ago)
So... this is permanent?
FLORIDAJESUSBOY 777 (10 months ago)
I have a side effect from the medicine called derealization and short term loss of memory. My question is if this medicine can cause a genetic defect. Could this also cause harm to my future children
卯十山 (1 year ago)
I think your video is based on this research https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857115/. However, this article is likely more focus on the "benefits" of this effect to treat adhd, but not 'permanent brain damage'. It is also hard to say the cause of side effects of this medicine is related to NMDA receptor rather than the volume change of Norepinephrine or other neurotransmitters in brain. And, in the use of human being, it is also very rare to find continuous long-term effects after interrupting the use of Strattera.
卯十山 (1 year ago)
Do you mind to offer the info. of the academic article related to this research? Otherwise, it could be considered as a bit “alarmism” .
vfddcv (1 year ago)
Whats the healthiest solution to adhd from the drugs and supps available in your opinion?my md doesnt know jack he just prescribes
Ink Spots (1 year ago)
Well as we know "normal" before Strattera wasn't cutting it so maybe it will be an improvement to be altered.
FrancesBaconandEggs (1 year ago)
Ink Spots amen to this. Strattera is the only drug that has changed me from the wreck I used to be.
Drew Thomas (1 year ago)
Tried Vyvanse, worked great for a week until the agitation and aggression became too intense, making me snap at everybody and eager to fight. Now my doc has prescribed me this. I haven't taken any yet as I didn't have enough money to fill the script and wanted to do some research first. SO GLAD I came to this video first. I'm gonna tell my doc I just want good ol' amphetamine salts (adderall) and to miss me with this bullshit. THANK YOU.
Deathful Turtle (1 year ago)
i fucking hated this shit ! it made me drowsy and irritable im still trying to fight for getting on adderall (i have severe add and Aspergers)
UK Choi (1 year ago)
https://www.ncbi.nlm.nih.gov/pubmed/27857045 Clinical trials, even for children, long term-administered.
UK Choi (1 year ago)
And I have searched through papers on PubMed(keyword: atomoxetine), from latest studies. They overall claims this drug is net positive in mechanisms and in terms. I think you should upload follow-ups to reorganize your claims. This is not clinical based, mice.
UK Choi (1 year ago)
I find your statements are well-organized and helpful for me who is taking 40mg Strattera often. Sir, however I think your remarks are quite radical or new in that they reverse general findings about Strattera still found. I ask you to substantiate a lot on this topic and it could be better.
daroke (1 year ago)
Can you provide more information about how Strattera works, the risks and what to watch out for? I'm fine on Straterra for 6 weeks but scared it could hurt me in de long run. It's difficult to interpreted papers.
King David (1 year ago)
I don't understand, is it good, or is it bad?
josh (1 year ago)
i made a video on how i felt the first week and planning.to quiet asap hate the side effects
Boom (2 years ago)
4:40 is a great example. "altering the leg of chairs forever"
thevisi0nary (2 years ago)
Thank you for this video, I was considering trying this medication for adhd because vyvanse is too stimulating. Would you say that this drug is not safe enough to try compared to something like intuniv?
Alec The Mack (2 years ago)
So how does this affect people? I just got prescribed 20 milligrams of Strattera how will this affect me?
Boom (2 years ago)
Great video. Can you also explain this picture? http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421042/figure/F1/ I feel it helps us undestand the big picture of stuff you are talking about. Thanks,
Boom (2 years ago)
how can we test people for "dysregulated glutamatergic metabolism " being their cause of ADHD or not??!
Boom (2 years ago)
" leading to altered development of synaptic composition"......!!!!
ruth b (2 years ago)
What are the side effects?
Mary Elizabeth (2 years ago)
1:41 gene expression significantly reduced? What does this mean exactly? 4:25 less sub-units? So is this going to hurt people's brain function?
SuperJakey92 (2 years ago)
I took strattera for one week for some focus/ concentration issues. I was moderately depressed before. taking it, but had been using 5 htp to cope. Started taking it noticed aggression, increase anxiety and testicular swelling. stopped med after only one week. over the weekend I grew into an increased flight or fight panic. I could not sleep for 4 days straight, went to er 3 times. I had massive body tremors and shakes at er. Given adivan to help with anxiety and panic attacks until I see psychiatrist. still having mild tremors but getting better. And I'm frequently crying. Its hard for me to find more info on strattera, it seems I experienced all the severe side effects except for a seizure. With only being on this 7/8 days. How long do you think with drawl could bw? I've been off of it 9 days now. I appreciate any advice you can give me.
Pieter Van Durme (3 months ago)
SuperJakey92 hi, now two years later how are you feeling? I have exactly the same problem. The hardest thing is lack of enjoyment. Like I don’t enjoy sex anymore. Will it get better? Thanks
LegendaryGamingChannel (5 months ago)
SuperJakey92 me too
bluestudio67 (1 year ago)
I asked because I was being put on it. My concerns were justified. An hour after my first pill and I was dry heaving. It lasted two hours. I called the doc and told her I was flushing it down the toilet. She put me on another one which made me have a bad temper. I quit it after one week. Now I'm on Ritalin and the change is quite remarkable. I seem to tolerate it quite well. We'll see how it goes.
SuperJakey92 (1 year ago)
I'll check out your video
josh (1 year ago)
SuperJakey92 i made a video about it and i almost feel exactly like you described your side effects.. i hate and regret the moment i got on it
Daniel Tjener (2 years ago)
I have ADD and Im getting 100 mg atomoxetine a day, but let me see If I get this video right, what you are basically saying is that it will work in my prefrontal cortex as a noradrenaline reuptake inhubator? Just as It should..... But it will make my nmda receptors not functioning? And the side effects will be what? I have been on this med. For a year now and Im having no sideeffects from it, and it really helps me a lot, isn't that the whole idea? Excuse me If I havn't understood it correctly, but im from Denmark.
bluestudio67 (2 years ago)
Sounds like you've got it right to me. I was just put on it and have been reading about the side effects. Some people appear to do just fine on it and for others it is intolerable. I'm hoping it works as well for me. I'm about to find out. ;)
Spencer Newman (2 years ago)
do you think certain side affects could permanently affect someone who took it at an early age?
Brian Kivuti (2 years ago)
Wait. Does that make Strattera poison?? Crap.
young kristen (1 year ago)
I have ADD and my dr proscribed strattera. I’m scared to take it because I heard a lot of bad things. Should I take it.
Calvin25X (2 years ago)
There have been some studies regarding liver problems with Strattera as well.
Sons of Apollo (2 years ago)
No problem! If you have any other questions don't hesitate to ask and I will answer them if I am able. 
Brian Kivuti (2 years ago)
+Sons of Apollo mmmm... Thanks for the information!
Sons of Apollo (2 years ago)
+Brian Kivuti If you have a particular mechanistic problem that would be helped by reducing the functionality of NMDA receptors no, but if that is not the issue it is likely to do more harm than good.
Tricidouglas36 Norris (2 years ago)
What about adderall?
Tomas Keller (2 years ago)
A A Probably, amphetamine is known to mankind for around 100 years. We know pretty good what effects it has and how it alters brain function.
A A (2 years ago)
Sons of Apollo oh shit... so how long will I regain my former self back? 5 months? a year?? I take wellbutrin, straterra and buspar because I thought they were safer than Adderall and Vyvanse. is Vyvanse and Adderall safer?
Sons of Apollo (2 years ago)
+Tricidouglas36 Norris There are side effects to that as well. I made a video about it on my old channel, but I may make another one. https://www.youtube.com/watch?v=aEwCWn4WquA
Kyuhyun (2 years ago)
I have a question! Well I have ADD since I can remember but started taking treatment last year.. Last year I took Methlph.... (I think you know that med) I went up to 25 but I noticed I had anger issues the more I increased and I also had less of an apitite and lost 10. (I was 15) so I stopped taking it and got strattera (and right now I'm 16) and I am at a 50 but what's the difference in these meds? In meth I felt I was more focused but had lots of energy but was mad and strattera I'm calm sad less apitite in the morning but I get REALLY hungry at night and I am more sleepy! I feel like my ADD got worse after meds cuz I've noticed If I don't take them for two weeks I feel like I have a harder time concentrating.. Also what are the bad side effects of these meds to me when u grow up?? Is it bad if I stoped taking them for two -3 months ? And is this the cause why I'm anemic?
Kyuhyun (2 years ago)
+Sons of Apollo yes I'm laughing in Espanol lol jeje means hehe but the jeje looks better... Oki lol check it out! Thanks!:D
Sons of Apollo (2 years ago)
Are you laughing in Spanish? I was the same when I was a kid, very much into astronomy. There is a program you might like, its called Celestia. http://www.shatters.net/celestia/
Kyuhyun (2 years ago)
+Sons of Apollo Thanks! I get it now jeje:D and I watched the video jaja and i haven't been through those words in biology:/ jaja I'm more into earth in space science than I am into biology lol
Sons of Apollo (2 years ago)
+Magi Cruz Methylphenidate is guessing, also known as Ritalin or Concerta. Those effects are very common most people will experience them to some degree, how strongly varies by individual. The difference is in how they work. Methylphenidate increases focus by acting on the central nervous system by increasing the neurotransmitters that activate it. Strattera works in a two ways. In increases attention by using the peripheral nervous system, which is everything outside the brain more or less, by increasing the neurotransmitters that activate that. (If you learned about the fight or flight response in biology its sort of like that) and by making genetic changes which I explained in the video.I made a video about Strattera vs Vyvanse (which is very similar to Adderall). While its not quite the same as methylphenidate, they try to do the same thing in but in different ways and may help you to understand the differences in effects. Methylphenidate vs Strattera would be very similar.https://www.youtube.com/watch?v=AmSZJ1YTaGMYes attention problems do seem to get worse long term with medication while people are not on it. How this happens is different by drug. I did one for methylphenidate, which should give you a basic idea of how it works.https://www.youtube.com/watch?v=qwNMMR2Ji6cWhat the effects are on developing brains are very different from a fully developed on. They certainly have an impact and there are many studies on the subject. Maybe I'll make a video on it sometime, because it would be quite a long discussion and I don't have all the data in front of me.Bad is a relative term. None of these drugs are good or bad they are tools. You just need to determine weather you need them or not. Think of amputating someone's arm. Is it bad or good? If they have gangrene and the arm can't be saved its a good thing, because otherwise its going to kill them. If they don't have a problem like that, ..well its probably best not to do that.Neither of those should make people anemic, did you mean something else? Sorry this was so long, I just haven't made any videos on those subjects (which are very important considerations). If you don't understand something let me know and I can try to explain it in a more simple way.
Kyuhyun (2 years ago)
Also when I took meth if wake myself up because I'd have little seizure like only 4 second ones
Marcus Schmück (2 years ago)
Is this change good or bad and why? Thanks.
Sons of Apollo (2 years ago)
+Marcus Schmuck Depends on what is causing the person's issue. If over reactivity of a certain receptor is the cause, then making those receptors less effective will be helpful. If something else were the cause, say depression or a viral infection, then its likely to do more harm than good.
Christopher Barth (2 years ago)
Excellent video!! I hope you do some videos soon!
Soggy Donuts (2 years ago)
Hello, sir. I am glad that you are still making videos. I've just discovered your channel after searching for videos on Vyvanse (I have ADD). Excellent video.
Sons of Apollo (2 years ago)
+Cæcilia Athena Thanks appreciate it, if you keep watching, I'll keep making them.
tandlast (2 years ago)
Thank you for explaining this study, I'm curious what prompted your interest in this study? When I first watched the video I thought when I looked at the study it would be very recent, but I was surprised it was from 2013. How did this come to your attention... can you point us to more info on this?
Sons of Apollo (2 years ago)
+tandlast I'm just a prolific reader; I saw the study and remember what many people had said about the effects seeming to last beyond the treatment period and decided to read it. I don't know of any other similar studies, there may be, but it would not at all surprise me if that study is unique.
Vít Vanžura (2 years ago)
I fight now with appetite. My dosage was reduced 2 weeks ago (60->40) and I feel like I am gonna eat each every cow I meet (@60mg i ate quite low). Do you think it's gonna stop after period of time? I used side effects loss weight and appetite as wished effect.
Sons of Apollo (2 years ago)
+Vít Vanžura Its hard to say, everyone's genes are different. Some of the effects of Strattera are due to the more immediate blocking of the NET and the rest to the genetic changes. Only time will tell.

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