Well, overall I got the point but I am curious why astrocytes not mentioned > Astrocyte modulation would play a helpful role in keeping synapse loud and pronounced . Yet astrocytes also work on homeostasis.. Is the implication here Donepezil inhibits acetylcholine uptake in astrocytes, does the recovered acetylcholine in the astrocyte return to post synaptic vesicles ? is there a Kreb response from astrocyte nucleus ??
So your brain is like an 18 wheeler that has lost the 18 wheels, that dementia damaged and only nine wheels are constantly being provided by Aricept and are being spread out to take the weight of the semi, so as long as you are taking your medication ( Aricept) your going to keep on traveling, of course not as smooth as original 18 wheels you once had before your dementia.Am I making any sense? Because my father is taking Aricept 10 mg per day.
Aricept is the worst med for dementia does not treat or prevent the disease. Two of the ingredients are reported to have Steel and gasoline. Some Physicians are trying to have it banned. Better to go with natural supplements that work better. While still may not cure it but no serious side effects and better results. Aricept is really a 400 million dollar profit for the pharmaceutical companies and no help for the patient at all. I am a caregiver for a dementia patient and we have checked into this and nothing nut bad luck with Aricept and haven't met any others with families who have had good results either. Do not keep your loved ones on this med.
It varies from person to person. Unfortunately, a lot of treatment with Alzheimer's is just trial and error. Unless Aricept/Donepezil was being taken with another medication then I'm not sure it could contribute to making the situation worse, but it might make your Grandmother unwell. I wish her all the best in a tough time <3